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Browsing SoAS - Scholarly Publications by Author "Mouneimne, Ghassan"

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Browsing SoAS - Scholarly Publications by Author "Mouneimne, Ghassan"

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  • Cofilin determines the migration behavior and turning frequency of metastatic cancer cells 
    Sidani, Mazen; Wessels, Deborah; Mouneimne, Ghassan; Ghosh, Mousumi; Goswami, Sumanta; Sarmiento, Corina; Wang, Weigang; Kuhl, Spencer; El-Sibai, Mirvat; Backer, Jonathan M.; Eddy, Robert; Soll, David; Condeelis, John (2015-11-09)
    We have investigated the effects of inhibiting the expression of cofilin to understand its role in protrusion dynamics in metastatic tumor cells, in particular. We show that the suppression of cofilin expression in MTLn3 ...
  • The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration 
    Yip, Shu-Chin; El-Sibai, Mirvat; Coniglio, Salvatore J.; Mouneimne, Ghassan; Eddy, Robert J.; Drees, Beth E.; Neilsen, Paul O.; Goswami, Sumanta; Symons, Marc; Condeelis, John S.; Backer, Jonathan M. (2015-11-09)
    Cell migration involves the localized extension of actinrich protrusions, a process that requires Class I phosphoinositide 3-kinases (PI 3-kinases). Both Rac and Ras have been shown to regulate actin polymerization ...

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