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Gilbert and Rose-Marie Chagoury School of Medicine: Recent submissions

  • Hemodynamic relationship between intracranial aneurysm and carotid stenosis 
    Jou, Liang-Der; Shaltoni, Hashem M.; Morsi, Hesham; Mawad, Michel E. (2019-07-10)
    Objective: Coexistence of both an intracranial aneurysm and a stenosis at the same internal carotid artery is infrequent, but it may complicate therapeutic management of either disease. It is unclear if a stenosis plays ...
  • MR appearance of an orbital leiomyoma 
    Carrier, D.A.; Mawad, M.E.; Kirkpatrick, J.B. (2019-07-10)
    The authors describe the MR appearance of an intraconal orbital vascular leiomyoma that probably arose from smooth muscle in the wall of a vein. Cavernous hemangiomas, schwannomas, neurofibromas, and other well-encapsulated ...
  • An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity 
    Wang, Wei; Qiu, Xiuchun; Zhang, Fujun; Sun, Jin; Cameron, Arlin G.; Wendt, Juliet A.; Mawad, Michel E.; Ke, Shi (2019-07-10)
    Developing agents with ‘seek, treat and see’ capability is critical for personalized molecular medicine. Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for ...
  • Aneurysm ostium angle 
    Yasuda, R.; Arat, A.; Strother, C.M.; Aagaard-Kienitz, B.; Niemann, D.; Mohamed, A.; Royalty, K.; Pulfer, K.; Taki, W.; Mawad, M.E. (2019-07-10)
    BACKGROUND AND PURPOSE: There is no satisfactory parameter that can predict the need for assistant devices for endovascular aneurysm coiling. Our aim was to evaluate the utility of MOA as a predictor of the need for ...
  • Timing and size of flow impingement in a giant intracranial aneurysm at the internal carotid artery 
    Jou, Liang-Der; Mawad, Michel E. (2019-07-10)
    Flow impingement is regarded as a key factor for aneurysm formation and rupture. Wall shear stress (WSS) is often used to evaluate flow impingement even though WSS and impinging force are in two different directions; ...
  • Metal coverage ratio of pipeline embolization device for treatment of unruptured aneurysms 
    Jour, Liang-Der; Chintalapani, Gouthami; Mawad, Michel E. (2019-07-10)
    Background and purpose The metal coverage ratio (MCR) of a flow diverter influences the intra-aneurysmal hemodynamics; a high MCR will occlude an aneurysm early, while a low MCR may delay aneurysm occlusion. The true MCR ...
  • Growth rate and rupture rate of unruptured intracranial aneurysms: a population approach 
    Jour, Liang-Der; Mawad, Michel E. (2019-07-10)
    Background Understanding aneurysm growth rate allows us to predict not only the current rupture risk, but also accumulated rupture risk in the future. However, determining growth rate of unruptured intracranial aneurysms ...
  • Stent-assisted coiling of intracranial aneurysms aided by virtual parent artery reconstruction 
    Karmonik, Christof; Strother, Charles M.; Chen, Xiaoyan; Deinzer, Frank; Kluczunik, Richard; Mawad, Michel E. (2019-07-09)
    Summary: The availability of stents designed specifically for use in the intracranial vasculature has increased the use of stent-assisted coiling for treatment of wide-necked and complex intracranial aneurysms. We present ...
  • Paraspinal arteriovenous malformations in children 
    Kitagawa, Ryan S.; Mawad, Michel E.; Whitehead, William E.; Curry, Daniel J.; Luersen, Thomas G.; Jea, Andrew (2019-07-09)
    Arteriovenous malformations (AVMs) within the spinal canal and in the paraspinal region are unusual. Spinal cord and dural AVMs or arteriovenous fistulas have been the subject of numerous reports, but paraspinal malformations ...
  • Computed tomography of primitive neuroectodermal tumors 
    Ganti, S.R.; Silver, A.J.; Diefenbach, P.; Hilal, S.K.; Mawad, M.E.; Sane, P. (2019-07-09)
    The primitive neuroectodermal tumor is a neoplasm of young individuals that occurs predominantly in the supratentorial compartment. It appears on computed tomography as a bulky mass, often with calcification with predominantly ...
  • Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm 
    Jou, Liang-Der; Mawad, Michel E. (2019-07-09)
    Stents play an important role in management of cerebral aneurysms. A stent reconstructs the parent artery, assists coil embolization, and decreases flow activity within an aneurysm. However, an in-stent stenosis often ...
  • Patterns of spinal cord atrophy by metrizamide CT 
    Mawad, M.E.; Hilal, S.K.; Fetell, M.R.; Silver, A.J.; Ganti, S.R.; Sane, P. (2019-07-09)
    Forty patients with cervical myelopathy underwent high-resolution computed tomography (CT) with intrathecal administration of metrizamide for evaluation of cervical spinal cord atrophy. Thirty of them showed evidence of ...
  • Computed tomography of the brain stem with intrathecal metrizamide. Part I 
    Mawad, M.E.; Silver, A.J.; Hilal, S.K.; Ganti, S.R. (2019-07-09)
    In summary, the anatomic details of the brain stem are exquisitely demonstrated with metrizamide CT. The obex is the zone of transition from the closed medulla, which has a conical pear-shaped appearance to the quadriconcave ...
  • Cross-flow at the anterior communicating artery and its implication in cerebral aneurysm formation 
    Jou, Liang-Der; Lee, Doek Hee; Mawad, Michel E. (2019-07-09)
    The anterior communicating artery (ACoA) is an important element of the circle of Willis. While the artery itself is short and small, a large number of intracranial aneurysms can be found at the ACoA. Four subject-specific ...
  • Focal headache during balloon inflation in the vertebral and basilar arteries 
    Nichols III, Fenwick; Mawad, Michel; Mohr, j.P.; Hilal, Sadek; Adams, Robert J. (2019-07-09)
    SYNOPSIS Background and Purpose: Headache may be seen in acute cerebrovascular disease. The significance of localized headache in association with vertebrobasilar disease has not been recognized. Summary of Report: ...
  • Incidence and clinical implications of carotid branch occlusion following treatment of internal carotid artery aneurysms with the pipeline embolization device 
    Vedantam, Aditya; Rao, Vikas Y.; Shaltoni, Hashem M.; Mawad, Michel E. (2019-07-09)
    BACKGROUND: The use of flow diverters such as the pipeline embolization device (PED) for treatment of intracranial aneurysms carries the risk of side branch occlusion. OBJECTIVE: To determine the incidence and clinical ...
  • CT and angiography of primary extradural juxtasellar tumors 
    Moore, T.; Ganti, S.R.; Mawad, M.E.; Hilal, S.K. (2019-07-09)
    The computed tomographic and angiographic features of 15 histologically proven primary extradural juxtasellar tumors were retrospectively reviewed. Five chordomas were characterized by prominent bone erosion and a significant ...
  • Metastatic adenocarcinoma to the brain 
    Carrier, D.A.; Mawad, M.E.; Kirkpatrick, J.B.; Schmid, M.F. (2019-07-09)
    PURPOSE To describe the appearance on T2-weighted scans of metastatic adenocarcinoma to the brain and to show that the hypointensity frequently associated with these lesions is not related to the presence of mucin, blood ...
  • Histopathologic findings in human cerebral aneurysms embolized with platinum coils 
    Ishihara, Shoichiro; Mawad, Michel E.; Ogata, Kentaro; Suzuki, Chihiro; Tsuzuki, Nobusuke; Katoh, Hiroshi; Ohnuki, Akira; Miyazawa, Takahito; Nawashiro, Hiroshi; Kaji, Tatsumi; Shima, Katsuji (2019-07-09)
    This report describes 2-week and 20-month histopathologic findings in small aneurysms embolized with platinum coils. Electron microscopy showed the presence of endothelial cells encroaching on the platinum coils at the ...
  • Cross-over technique for horizontal stenting of an internal carotid bifurcation aneurysm using a new self-expandable stent 
    Benndorf, Goetz; Klucznick, Richard P.; Meyer, Denise; Strother, Charles M.; Mawad, Michel E. (2019-07-09)
    OBJECTIVE AND IMPORTANCE: To describe the use of a newly available self-expandable stent in a cross-over approach for treatment of a large, wide-necked carotid termination aneurysm. CLINICAL PRESENTATION: A 58-year-old ...

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