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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Zorzi, Daria"

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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Zorzi, Daria"

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  • Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases 
    Ribero, David; Wang, Huamin; Donadon, Matteo; Zorzi, Daria; Thomas, Melanie; Eng, Cathy; Chang, David; Curley, Steven; Abdalla, Eddie; Ellis, Lee; Vauthey, Nicolas (2015-11-16)
    BACKGROUND. The current study evaluated the effect of bevacizumab added to fluoropyrimidine-plus-oxaliplatin (5FU/OX) chemotherapy for colorectal liver metastases (CLM) on the pathologic response and nontumorous liver ...
  • Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases 
    Vauthey, Nicolas; Pawlik, Timothy; Ribero, Dario; Wu, Tsung-Teh; Zorzi, Daria; Hoff, Paulo; Xiong, Henry; Eng, Cathy; Lauwers, Gregory; Mino-Kenudson, Mari; Risio, Mauro; Muratore, Andrea; Capussotti, Lorenzo; Curley, Steven; Abdalla, Eddie (2015-11-12)
    Purpose Chemotherapy before resection of hepatic colorectal metastases (CRM) may cause hepatic injury and affect postoperative outcome. Patients and Methods Four hundred six patients underwent hepatic resection of CRM ...
  • Chemotherapy With Bevacizumab Does Not Affect Liver Regeneration After Portal Vein Embolization in the Treatment of Colorectal Liver Metastases 
    Zorzi, Daria; Shin Chun, Yun; Madoff, David; Abdalla, Eddie; Vauthey, Jean-Nicolas (2015-11-17)
    Background Blockage of vascular endothelial growth factor (VEGF) in murine models has been shown to impair liver regeneration after partial hepatectomy. The aim of this study was to evaluate the effects of chemotherapy ...
  • Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases 
    Abdalla, Eddie; Zorzi, Daria; Mullen, John; Pawlik, Timothy; Andres, Axel; Muratore, Andrea; Curley, Steven; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-12)
    Some investigators have suggested that wedge resection (WR) confers a higher incidence of positive margins and an inferior survival compared with anatomic resection (AR) of colorectal liver metastases (CLM). We sought to ...
  • Critical Appraisal of the Clinical and Pathologic Predictors of Survival After Resection of Large Hepatocellular Carcinoma 
    Abdalla, Eddie; Pawlik, Timothy; Poon, Ronnie; Zorzi, Daria; Ikai, Iwao; Curley, Steven; Nagorney, David; Belghiti, Jacques; Oi-Lin Ng, Irene; Yamaoka, Yoshio; Lauwers, Gregory; Vauthey, Nicolas (2015-11-11)
    Hypothesis A subset of patients with hepatocellular carcinoma (HCC) with a diameter of 10 cm or larger may benefit from hepatic resection. Design Retrospective study of a multi-institutional database. Setting Five ...
  • Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases 
    Pawlik, Timothy; Scoggins, Charles; Zorzi, Daria; Abdalla, Eddie; Andres, Axel; Eng, Cathy; Curley, Steven; Loyer, Evelyne; Muratore, Andrea; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-11)
    Objective: To evaluate the influence of surgical margin status on survival and site of recurrence in patients treated with hepatic resection for colorectal metastases. Methods: Using a multicenter database, 557 ...
  • Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases 
    Kishi, Yoji; Zorzi, Daria; Contreras, Carlo; Maru, Dipen; Kopetz, Scott; Ribero, Dario; Motta, Manuela; Ravarino, Nicoletta; Risio, Mauro; Curley, Steven; Abdalla, Eddie; Capussotti, Lorenzo; Vauthey, Jean-Nicolas (2015-11-19)
    Background The optimal duration, safety, and benefit of preoperative chemotherapy in patients with colorectal liver metastases (CLM) are unclear. We evaluated the association between the duration of preoperative chemotherapy ...
  • Hepatic Insufficiency and Mortality in 1,059 Noncirrhotic Patients Undergoing Major Hepatectomy 
    Mullen, John; Ribero, Dario; Reddy, Srinevas; Donadon, Matteo; Zorzi, Daria; Gautam, Shiva; Abdalla, Eddie; Curley, Steven; Capussotti, Lorenzo; Clary, Bryan; Vauthey, Nicolas (2015-11-16)
    Background To establish a reliable definition of postoperative hepatic insufficiency (PHI) in noncirrhotic patients undergoing major hepatectomy. No standard definition of PHI has been established, but one is essential ...
  • Hepatic Resection for Metastatic Melanoma 
    Abdalla, Eddie; Pawlik, Timothy; Zorzi, Daria; Clary, Bryan; Gershenwald, Jeffrey; Ross, Merrick; Aloia, Thomas; Curley, Steven; Camacho, Luis; Capussotti, Lorenzo; Elias, Dominique; Vauthey, Nicolas (2015-11-12)
    Background Resection of melanoma metastatic to the liver remains controversial. We evaluated the efficacy of hepatic resection in patients with metastatic ocular and cutaneous melanoma and assessed factors that could ...
  • Major hepatic resection for hepatocellular carcinoma with or without portal vein embolization 
    Palavecino, Martin; Chun, Yun; Madoff, David; Zorzi, Daria; Kishi, Yoji; Kaseb, Ahmed; Curley, Steven; Abdalla, Eddie; Vauthey, Jean-Nicolas (2015-11-18)
    Background Preoperative portal vein embolization (PVE) is performed to minimize perioperative risks of major hepatic resection for hepatocellular carcinoma (HCC), but its effects on tumor growth are ill defined. ...
  • Pathologic Response to Preoperative Chemotherapy 
    Blazer III, Dan; Kishi, Yoji; Maru, Dipen; Shin Chun, Yun; Overman, Micheal; Fogelman, David; Eng, Cathy; Chang, David; Wang, Huamin; Zorzi, Daria; Ribero, Dario; Ellis, Lee; Glover, Katrina; Wolff, Robert; Curley, Steven; Abdalla, Eddie; Vauthey, Nicolas (2015-11-16)
    Purpose The primary goal of this study was to evaluate whether pathologic response to chemotherapy predicts patient survival after preoperative chemotherapy and resection of colorectal liver metastases (CLM). The secondary ...
  • Resection of Hepatic Colorectal Metastases Involving the Caudate Lobe 
    Abdalla, Eddie; Ribero, Dario; Pawlik, Timothy; Zorzi, Daria; Curley, Steven; Muratore, Andrea; Andres, Axel; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-12)
    Purpose: To examine clinical features and outcome of patients who underwent hepatic resection for colorectal liver metastases (LM) involving the caudate lobe. Patients and Methods: Consecutive patients who underwent ...
  • Simultaneous Resections of Colorectal Cancer and Synchronous Liver Metastases 
    Reddy, Srinevas; Pawlik, Timothy; Zorzi, Daria; Gleisner, Ana; Ribero, Dario; Assumpc ao, Lia; Barbas, Andrew; Abdalla, Eddie; Choti, Micheal; Vauthey, Nicolas; Ludwig, Krik; Mantyh, Christopher; Morse, Micheal; Clary, Bryan (2015-11-16)
    Background The safety of simultaneous resections of colorectal cancer and synchronous liver metastases (SCRLM) is not established. This multi-institutional retrospective study compared postoperative outcomes after ...
  • Solitary colorectal liver metastasis 
    Abdalla, Eddie; Vauthey, Nicolas; Loyer, Evelyne; Ribero, Dario; Pawlik, Timothy; Wei, Steven; Zorzi, Daria (2015-11-12)
    Background Hepatic resection (HR) and radiofrequency ablation (RFA) have been proposed as equivalent treatments for colorectal liver metastasis. Hypothesis Recurrence patterns after HR and RFA for solitary liver ...
  • Subtotal hepatectomy following neoadjuvant chemotherapy for a previously unresectable hepatocellular carcinoma 
    Abdalla, Eddie; Zorzi, Daria; Pawlik, Timothy; Brown, Thomas; Vauthey, Nicolas (2015-11-12)
    An awareness of variant hepatic vascular anatomy provides vital information in the preoperative evaluation of patients with hepatocellular carcinoma. The authors present a patient with unresectable hepatocellular carcinoma ...
  • Three Hundred and One Consecutive Extended Right Hepatectomies 
    Kishi, Yoji; Abdalla, Eddie; Chun, Yun Shin; Zorzi, Daria; Madoff, David; Wallace, Micheal; Curley, Steven; Vauthey, Jean-Nicolas (2015-11-17)
    Objective(s): This study aimed to determine the effect of preoperative liver volumetry on postoperative outcomes after extended right hepatectomy. Primary end point was to evaluate whether future liver remnant (FLR)/standardized ...
  • Timing of Multimodality Therapy for Resectable Synchronous Colorectal Liver Metastases 
    Reddy, Srinevas; Zorzi, Daria; Barbas, Andrew; Pawlik, Timothy; Ribero, Dario; Abdalla, Eddie; Choti, Micheal; Kemp, Clinton; Vauthey, Jean-Nicolas; Morse, Micheal; White, Rebecah; Clary, Bryan; Lum, Ying Wei (2015-11-18)
    The optimal timing of chemotherapy relative to resection of synchronous colorectal liver metastases (SCRLM) is not known. The objective of this retrospective multi-institutional study was to assess the influence of ...
  • Treatment of Large and Advanced Hepatocellular Carcinoma 
    Abdalla, Eddie; Denys, Alban; Hasegawa, Kiyoshi; Leung, Thomas; Makuushi, Masatoshi; Murthy, Ravi; Ribero, Dario; Zorzi, Daria; Vauthey, Nicolas; Torzilli, Guido (2015-11-16)
  • Two-Surgeon Technique for Hepatic Parenchymal Transection of the Noncirrhotic Liver Using Saline-Linked Cautery and Ultrasonic Dissection 
    Aloia, Thomas; Zorzi, Daria; Abdalla, Eddie; Vauthey, Nicolas (2015-11-11)
    Objective: The purpose of this study was to analyze our experience with saline-linked cautery in hepatic surgery. Summary Background Data: Safe and efficient hepatic parenchymal transection is predicated on the ...

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