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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Zalloua, Pierre A."

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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Zalloua, Pierre A."

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  • Haber, Marc; Platt, Daniel E.; Bonab, Maziar Ashrafian; Youhanna, Sonia C.; Soria-Hernanz, David F.; Martínez-Cruz, Begona; Douaihy, Bouchra; Ghassibe-Sabbagh, Michella; Rafatpanah, Hoshang; Ghanbari, Mohsen; Whale, John; Balanovsky, Oleg; Spencer Wells, R.; Comas, David; Tyler-Smith, Chris; Zalloua, Pierre A. (2019-07-25)
    Afghanistan has held a strategic position throughout history. It has been inhabited since the Paleolithic and later became a crossroad for expanding civilizations and empires. Afghanistan's location, history, and diverse ...
  • Alwan, Ahmad; Youhanna, Sonia C.; Platt, Daniel E.; El-Sibai, Mirvat; Yerezian, Joumana S.; Deeb, Mary E.; Khazen, Georges; Saade, Stephanie; Zreik, Tony G.; El Bayeh, Hamid; Maalouf, Assaad; Zalloua, Pierre A.; Abchee, Antoine (2015-12-17)
    Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. Previous reports correlating ALOX5AP gene variants and CAD showed conflicting results depending on the population ...
  • Platt, Daniel E.; Hariri, Essa; Salameh, Pascale; Helou, Mariana; Sabbah, Nada; Merhi, Mahmoud; Abchee, Antoine B.; Zalloua, Pierre A. (2019-06-03)
    Background: Waterpipe smoking is a rising global public health epidemic perceived by many users to be less harmful, though its toxicity overlaps or even exceeds that of cigarette smoking. Short-term cardiovascular changes ...
  • Karnib, Hussein H.; Sanna-Cherchi, Simone; Zalloua, Pierre A.; Medawar, Walid; D'Agati, Vivette D.; Lifton, Richard P.; Badr, Kamal; Gharavi, Ali G. (2019-07-19)
    Background. Familial aggregation of IgA nephropathy (IgAN) suggests that genetic factors contribute to the development of this trait. Because clinical manifestations in IgAN families are often limited to episodic haematuria, ...
  • Zalloua, Pierre A.; Buzayan, Jamal M.; Bruening, George (2019-07-19)
    Each of the two genomic RNAs of tobacco ringspot nepovirus is known to have a 5′-linked protein, the VPg. We report a simplified analysis of the covalent VPg-RNA connection that allowed us to identify the 5′ nucleotide ...
  • Deeb, Mary E.; Khazen, Georges; Zalloua, Pierre A.; Platt, Daniel E.; Ghassibe-Sabbagh, Michella; Cazier, Jean-Baptiste; Kamatani, Yoichiro; Salloum, Angelique K.; Hager, Jo¨rg; Youhanna, Sonia (2016-11-23)
    A main underlying pathology of coronary artery disease is the deposition of cholesterol in the arteries supplying blood to the heart that leads to stenosis and myocardial infarction. We tested if dyslipidemia is a risk ...
  • Zalloua, Pierre A.; Aoun, Elie; Koussa, Suzanne; Asfahani, Wissam S.Z.; Taher, Ali (2019-07-22)
    Thalassemia is a common inherited disease in the Mediterranean region. We here report a mutation new to the Lebanese population: the insertion of a G nucleotide at codons 8/9 [(+G) AAG‐TCT (Lys‐Ser)→AAG‐G‐TCT (β0)] of the ...
  • Azar, Sami T.; Zalloua, Pierre A.; Medlej, Rita; Halabi, George (2019-07-19)
    Genetic factors are involved in the development of diabetic nephropathy in type-1 diabetes. We are examining the association of the angiotensin-converting enzyme (ACE), insertion/deletion (I/D) polymorphism with the presence ...
  • Zalloua, Pierre A.; Deeb, Mary; Kattara, Mireille M.; Araj, George F.; Samaha-Kfoury, Joumana; Shbakloe, Hadia; Kanj, Souha S.; Khalife, Simon (2016-11-18)
    This study aimed at developing a real-time polymerase chain reaction (PCR) assay for the rapid diagnosis of human brucellosis on clinical specimens. Three assays with hybridization probe detection on the LightCycler™ ...
  • Salem, Ziad; Zalloua, Pierre A.; Chehali, Aref; Bitar, Nizar; Abboud, Miguel; kadri, Adel; Chami, Beatrice; Bazarbachi, Ali (2019-07-19)
    Imatinib mesylate treatment is highly effective in chronic myeloid leukaemia and recent data have suggested that imatinib mesylate is also effective in the treatment of idiopathic hypereosinophilicsyndrome (HES). Six ...
  • Henn, Brenna M.; Botigue, Laura R.; Gravel, Simon; Wang, Wei; Brisbin, Abra; Byrnes, Abra; Bymes, Jake K.; Fadhlaoui-Zid, Karina; Zalloua, Pierre A.; Moreno-Estrada, Andres; Bertranpetit, Jaume; Bustamante, Carlos D.; Comas, David (2019-07-19)
    North African populations are distinct from sub-Saharan Africans based on cultural, linguistic, and phenotypic attributes; however, the time and the extent of genetic divergence between populations north and south of the ...
  • Ammar, Walid; Kdouh, Ola; Hammoud, Rawan; Hamadeh, Randa; Harb, Hilda; Ammar, Zeina; Atun, Rifat; Christiani, David; Zalloua, Pierre A. (2019-07-25)
    Background Between 2011 and 2013, the Lebanese population increased by 30% due to the influx of Syrian refugees. While a sudden increase of such magnitude represents a shock to the health system, threatening the continuity ...
  • Azar, Sami T.; Salti, Ibrahim; Zantout, Mira S.; Shahine, Carmen H.; Zalloua, Pierre A. (2019-07-19)
    Leptin is the protein product of the obese (ob) gene, a lipostatic hormone that contributes to body weight regulation through suppressing appetite and/or stimulating energy expenditure in humans and/or rodents. In humans, ...
  • Abchee, Antoine; El-Sibai, Mirvat; Youhanna, Sonia; Yeretzian, Joumana S.; Hanine, Estephan; Makhoul, Nadine J.; Puzantian, Houry; Sawaya, Jaber; Nasrallah, Antoine; Rebeiz, Abdallah G.; Zreik, Tony G.; Azar, Sami T.; Zalloua, Pierre A. (2017-07-27)
    Background: Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation are important modulators of coronary artery disease (CAD). Objective: This study investigated the association between allelic ...
  • Zalloua, Pierre A.; Platt, Daniel E.; El Sibai, Mirvat; Khalife, Jade; Makhoul, Nadine; Haber, Marc; Xue, Yali; Izaabel, Hassan; Bosch, Elena; Adams, Susan M.; Arroyo, Eduardo; Lopez-Parra, Ana Maria; Aler, Mercedes; Picornell, Antonia; Ramon, Misericordia; Jobling, Mark A.; Comas, David; Bertranpetit, Jaume; Tyler-Smith, Chris (2019-07-18)
    The Phoenicians were the dominant traders in the Mediterranean Sea two thousand to three thousand years ago and expanded from their homeland in the Levant to establish colonies and trading posts throughout the Mediterranean, ...
  • Zalloua, Pierre A.; Hsu, Yi-Hsiang; Terwedow, Henry; Zang, Tonghua; Tang, Genfu; Li, Zhiping; Hong, Xiumei; Azar, Sami T.; Wang, Binyan; Bouxsein, Mary L.; Brain, Joseph; Cummings, Steven R.; Rosen, Clifford J.; Xu, Xiping (2019-07-18)
    Objectives Over the past decade, dietary choices and nutrition have proven to be major modulators of bone mineral density (BMD) in men and women. We investigated environmental determinants, specifically dietary habits, ...
  • Stolzenburg, Svenja; Lauridsen, Micheal B.; Toft, Henrik; Zalloua, Pierre A.; Baunsgaard, Dorrit (2019-07-22)
    NMR based metabolic profiling of blood samples in epidemiological studies can be used for molecular phenotyping and biomarker discovery. Often metabolic changes in blood are more subtle and demand a high quality spectrum ...
  • Buzayan, Jamal M.; Tol, Hans Van; Zalloua, Pierre A.; Bruening, George (2019-07-19)
    A small satellite RNA of tobacco ringspot virus (sTRSV RNA) generates circular and linear molecules of unit length and repetitive sequence, linear multimers during replication. The phosphodiester junction joining the unit ...
  • Deloukas, Panos; Zalloua, Pierre A. (2019-07-25)
    Coronary artery disease (CAD) is the commonest cause of death. Here, we report an association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching genome-wide significance, taking the number of ...
  • Ghassibe-Sabbagh, Michella; Deeb, Mary; Saloum, Angelique K.; Hirbli, Kamal; Ahdab, Rechdi; Zalloua, Pierre A.; Nemr, Rita; Mouzaya, Francis; Chami, Youssef; Akle, Yasmine; Platt, Daniel E. (2016-06-14)
    Background: The burden of diabetes in Lebanon requires well-targeted interventions for screening type 2 diabetes mellitus (T2DM) and prediabetes and prevention of risk factors. Newly recruited 998 Lebanese individuals, ...

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