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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Varin, Audrey"

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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Varin, Audrey"

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  • Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy 
    Hanna, Rita; Nour-Eldine, Wared; Saliba, Youakim; Dagher-Hamalian, Carole; Hachem, Pia; Abou-Khalil, Pamela; Mika, Delphine; Varin, Audrey; El Hayek, Magali Samia; Pereira, Laëtitia; Fares, Nassim; Vandecasteele, Grégoire; Abi-Gerges, Aniella (2021-12-23)
    Aim Diabetic cardiomyopathy (DCM) accomodates a spectrum of cardiac abnormalities. This study aims to investigate whether DCM is associated with changes in cyclic adenosine 3′-5′ monophosphate (cAMP) signaling, particularly ...
  • Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals 
    Abi-Gerges, Aniella; Richter, Wito; Lefebvre, Florence; Mateo, Philippe; Varin, Audrey; Heymes, Chrisrophe; Samuel, Jane-Lise; Lugnier, Claire; Conti, Marco; Fischmeister, Rodolphe; Vandecasteele, Gregoire (2017-10-19)
    Rationale: Multiple cyclic nucleotide phosphodiesterases (PDEs) degrade cAMP in cardiomyocytes but the role of PDEs in controlling cAMP signaling during pathological cardiac hypertrophy is poorly defined. Objective: ...

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