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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Pawlik, Timothy"

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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Pawlik, Timothy"

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  • Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases 
    Vauthey, Nicolas; Pawlik, Timothy; Ribero, Dario; Wu, Tsung-Teh; Zorzi, Daria; Hoff, Paulo; Xiong, Henry; Eng, Cathy; Lauwers, Gregory; Mino-Kenudson, Mari; Risio, Mauro; Muratore, Andrea; Capussotti, Lorenzo; Curley, Steven; Abdalla, Eddie (2015-11-12)
    Purpose Chemotherapy before resection of hepatic colorectal metastases (CRM) may cause hepatic injury and affect postoperative outcome. Patients and Methods Four hundred six patients underwent hepatic resection of CRM ...
  • Comparison between hepatic wedge resection and anatomic resection for colorectal liver metastases 
    Abdalla, Eddie; Zorzi, Daria; Mullen, John; Pawlik, Timothy; Andres, Axel; Muratore, Andrea; Curley, Steven; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-12)
    Some investigators have suggested that wedge resection (WR) confers a higher incidence of positive margins and an inferior survival compared with anatomic resection (AR) of colorectal liver metastases (CLM). We sought to ...
  • Critical Appraisal of the Clinical and Pathologic Predictors of Survival After Resection of Large Hepatocellular Carcinoma 
    Abdalla, Eddie; Pawlik, Timothy; Poon, Ronnie; Zorzi, Daria; Ikai, Iwao; Curley, Steven; Nagorney, David; Belghiti, Jacques; Oi-Lin Ng, Irene; Yamaoka, Yoshio; Lauwers, Gregory; Vauthey, Nicolas (2015-11-11)
    Hypothesis A subset of patients with hepatocellular carcinoma (HCC) with a diameter of 10 cm or larger may benefit from hepatic resection. Design Retrospective study of a multi-institutional database. Setting Five ...
  • Debunking dogma 
    Abdalla, Eddie; Pawlik, Timothy; Vauthey, Nicolas; Curley, Steven (2015-11-12)
    Treatment of four or more colorectal liver metastases (CRLMs) is controversial and remains a relative contraindication to surgery at some institutions. We sought to assess the outcome of patients with four or more CRLMs ...
  • Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases 
    Pawlik, Timothy; Scoggins, Charles; Zorzi, Daria; Abdalla, Eddie; Andres, Axel; Eng, Cathy; Curley, Steven; Loyer, Evelyne; Muratore, Andrea; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-11)
    Objective: To evaluate the influence of surgical margin status on survival and site of recurrence in patients treated with hepatic resection for colorectal metastases. Methods: Using a multicenter database, 557 ...
  • Hepatic Resection for Metastatic Melanoma 
    Abdalla, Eddie; Pawlik, Timothy; Zorzi, Daria; Clary, Bryan; Gershenwald, Jeffrey; Ross, Merrick; Aloia, Thomas; Curley, Steven; Camacho, Luis; Capussotti, Lorenzo; Elias, Dominique; Vauthey, Nicolas (2015-11-12)
    Background Resection of melanoma metastatic to the liver remains controversial. We evaluated the efficacy of hepatic resection in patients with metastatic ocular and cutaneous melanoma and assessed factors that could ...
  • Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma 
    Abdalla, Eddie; Pawlik, Timothy; Poon, Ronnie; Sarmiento, Juan; Lkai, Iwao; Curley, Steven; Nagorney, David; Belghiti, Jacques; Oi-Lin Ng, Irene; Yamaoka, Yoshio; Lauwers, Gregory; Vauthey, Nicolas (2015-11-10)
    The impact of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection on survival rates after resection of hepatocellular carcinoma (HCC) is controversial. The objective of this study was to determine whether serologic ...
  • Is extended hepatectomy for hepatobiliary malignancy justified? 
    Abdalla, Eddie; Vauthey, Nicolas; Pawlik, Timothy; Arens, James; Nemr, Rabih; Wei, Steven; Kennamer, Debra; Ellis, Lee; Curley, Steven (2015-11-11)
    Background: Extended hepatectomy may be required to provide the best chance for cure of hepatobiliary malignancies. However, the procedure may be associated with significant morbidity and mortality. Methods: We ...
  • Liver-Directed Surgery for Metastatic Squamous Cell Carcinoma to the Liver 
    Pawlik, Timothy; Gleisner, Ana Luiza; Bauer, Todd; Reddy, Srinevas; Clary, Bryan; Martin, Robert; Scoggins, Charles; Tanabe, Kenneth; Michealson, James; Kooby, David; Staley, Charles; Schulick, Richard; Vauthey, Nicolas; Abdalla, Eddie; Curley, Steven; Choti, Micheal; Elias, Dominique (2015-11-16)
    Background The role of hepatic resection for metastatic squamous cell carcinoma (SCC) remains unknown. The current study evaluates the role of hepatic resection in patients with metastatic SCC to the liver. Methods Between ...
  • Pretreatment assessment of hepatocellular carcinoma: expert consensus statement 
    Vauthey, Jean-Nicolas; Dixon, Elijah; Abdalla, Eddie; Helton, Scott; Pawlik, Timothy; Taouli, Bachir; Brouquet, Antoine; Adams, Reid (2015-11-19)
    Staging of hepatocellular carcinoma (HCC) is complex and relies on multiple factors including tumor extent and hepatic function. No single staging system is applicable to all patients with HCC. The staging of the American ...
  • A Proposed Staging System for Intrahepatic Cholangiocarcinoma 
    Nathan, Hari; Aloia, Thomas; Vauthey, Jean-Nicolas; Abdalla, Eddie; Zhu, Andrew; Schulick, Richard; Choti, Micheal; Pawlik, Timothy (2015-11-18)
    The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) staging system for liver cancer is based on data exclusively derived from hepatocellular carcinoma (HCC) patients and thus may be ...
  • Resection of Hepatic Colorectal Metastases Involving the Caudate Lobe 
    Abdalla, Eddie; Ribero, Dario; Pawlik, Timothy; Zorzi, Daria; Curley, Steven; Muratore, Andrea; Andres, Axel; Mentha, Gilles; Capussotti, Lorenzo; Vauthey, Nicolas (2015-11-12)
    Purpose: To examine clinical features and outcome of patients who underwent hepatic resection for colorectal liver metastases (LM) involving the caudate lobe. Patients and Methods: Consecutive patients who underwent ...
  • Results of a Single-Center Experience With Resection and Ablation for Sarcoma Metastatic to the Liver 
    Abdalla, Eddie; Pawlik, Timothy; Vauthey, Nicolas; Pollock, Raphael; Ellis, Lee; Curley, Steven (2015-11-12)
    Hypothesis A subset of patients with sarcoma liver metastasis may benefit from hepatic resection and/or ablation. Design Retrospective review of prospectively collected cancer center database records. Patients and ...
  • Simultaneous Resections of Colorectal Cancer and Synchronous Liver Metastases 
    Reddy, Srinevas; Pawlik, Timothy; Zorzi, Daria; Gleisner, Ana; Ribero, Dario; Assumpc ao, Lia; Barbas, Andrew; Abdalla, Eddie; Choti, Micheal; Vauthey, Nicolas; Ludwig, Krik; Mantyh, Christopher; Morse, Micheal; Clary, Bryan (2015-11-16)
    Background The safety of simultaneous resections of colorectal cancer and synchronous liver metastases (SCRLM) is not established. This multi-institutional retrospective study compared postoperative outcomes after ...
  • Solitary colorectal liver metastasis 
    Abdalla, Eddie; Vauthey, Nicolas; Loyer, Evelyne; Ribero, Dario; Pawlik, Timothy; Wei, Steven; Zorzi, Daria (2015-11-12)
    Background Hepatic resection (HR) and radiofrequency ablation (RFA) have been proposed as equivalent treatments for colorectal liver metastasis. Hypothesis Recurrence patterns after HR and RFA for solitary liver ...
  • Subtotal hepatectomy following neoadjuvant chemotherapy for a previously unresectable hepatocellular carcinoma 
    Abdalla, Eddie; Zorzi, Daria; Pawlik, Timothy; Brown, Thomas; Vauthey, Nicolas (2015-11-12)
    An awareness of variant hepatic vascular anatomy provides vital information in the preoperative evaluation of patients with hepatocellular carcinoma. The authors present a patient with unresectable hepatocellular carcinoma ...
  • Timing of Multimodality Therapy for Resectable Synchronous Colorectal Liver Metastases 
    Reddy, Srinevas; Zorzi, Daria; Barbas, Andrew; Pawlik, Timothy; Ribero, Dario; Abdalla, Eddie; Choti, Micheal; Kemp, Clinton; Vauthey, Jean-Nicolas; Morse, Micheal; White, Rebecah; Clary, Bryan; Lum, Ying Wei (2015-11-18)
    The optimal timing of chemotherapy relative to resection of synchronous colorectal liver metastases (SCRLM) is not known. The objective of this retrospective multi-institutional study was to assess the influence of ...
  • Tumor size predicts vascular invasion and histologic grade 
    Abdalla, Eddie; Pawlik, Timothy; Delman, Keith; Vauthey, Nicolas; Nagorney, David; Oi-Lin Ng, Irene; Yamaoka, Yoshio; Ikai, Iwao; Belghiti, Jacques; Lauwers, Gregory; Poon, Ronnie (2015-11-11)
    Vascular invasion and high histologic grade predict poor outcome after surgical resection or liver transplantation for hepatocellular carcinoma (HCC). Despite the known association between tumor size and vascular invasion, ...

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