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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Crane, Christopher"

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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Crane, Christopher"

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  • Aggressive Combined Modality Therapy for Recurrent Colorectal Cancer Involving the Duodenum and Pancreas 
    Overman, Micheal; Fogelman, David; Al-Kali, Aref; Crane, Christopher; Evans, Douglas; Abdalla, Eddie; Pisters, Peter; Kopetz, Scott; Eng, Cathy; Wolff, Robert (2015-11-17)
    We report 5 cases in which the recurrence of colorectal cancer (CRC) presented as a mass involving the duodenum and pancreas. The treatment approach for such recurrences is not standardized, and in particular, the benefits ...
  • Borderline Resectable Pancreatic Cancer 
    Katz, Matthew; Pisters, Peter; Evans, Douglas; Sun, Charlotte; Lee, Jeffrey; Fleming, Jason; Vauthey, Jean-Nicolas; Abdalla, Eddie; Crane, Christopher (2015-11-17)
    Background Patients with borderline resectable pancreatic adenocarcinoma (PA) include those with localized disease who have tumor or patient characteristics that preclude immediate surgery. There is no optimal treatment ...
  • Defined Clinical Classifications Are Associated with Outcome of Patients with Anatomically Resectable Pancreatic Adenocarcinoma Treated with Neoadjuvant Therapy 
    Tzeng, Ching-Wei; Fleming, Jason; Lee, Jeffrey; Xiao, Lianchun; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wolff, Robert; Varadhachary, Gauri; Fogelman, David; Crane, Christopher; Balachandran, Aparna; Katz, Matthew (2015-11-20)
    Background We previously introduced a classification system for patients with localized pancreatic adenocarcinoma that integrates assessments of tumor anatomy, cancer biology, and patient physiology. By means of this ...
  • Delayed Recovery after Pancreaticoduodenectomy 
    Abdalla, Eddie; Aloia, Thomas; Lee, Jeffrey; Vauthey, Nicolas; Wolff, Robert; Varadhachary, Gauri; Abbruzzese, James; Crane, Christopher; Evans, Douglas; Pisters, Peter (2015-11-12)
    Background Delayed recovery after pancreaticoduodenectomy (PD) is believed to preclude adjuvant therapy for approximately 30% of patients who undergo elective PD as initial treatment for pancreatic adenocarcinoma. This ...
  • Effect of Neoadjuvant Chemoradiation and Surgical Technique on Recurrence of Localized Pancreatic Cancer 
    Katz, Matthew; Wang, Huamin; Balachandran, Aparna; Bhosale, Priya; Crane, Christopher; Wang, Xuemei; Pisters, Peter; Lee, Jeffrey; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wolff, Robert; Abbruzzese, James; Varadhachary, Gauri; Chopin-Laly, Xavier; Chamsangavej, Chulsip; Fleming, Jason (2015-11-20)
    Objectives To determine the influence of neoadjuvant chemoradiation and standardized dissection of the superior mesenteric artery upon the oncologic outcome of patients with localized pancreatic adenocarcinoma. Methods One ...
  • Extrahepatic Bile Duct Adenocarcinoma 
    Borghero, Yerko; Crane, Christopher; Szklaruk, Janio; Oyarzo, Mauricio; Curley, Steven; Pisters, Peter; Evans, Douglas; Abdalla, Eddie; Thomas, Melanie; Das, Prajnan; Wistuba, Ignacio; Krishnan, Sunil; Vauthey, Nicolas (2015-11-16)
    Background Patients with resected extrahepatic bile duct adenocarcinoma who have microscopically positive resection margins and/or pathologic locoregional nodal involvement (R1pN1) have a high-risk of locoregional recurrence, ...
  • Impact of Resection Status on Pattern of Failure and Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma 
    Raut, Chandrajit; Tseng, Jennifer; Sun, Charlotte; Wang, Huamin; Wolff, Robert; Crane, Christopher; Vauthey, Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-16)
    Objective: To better understand the impact of a microscopically positive margin (R1) on patterns of disease recurrence and survival after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma. Summary Background ...
  • Localized adenocarcinoma of the pancreas: the rationale for preoperative chemoradiation 
    Abdalla, Eddie; Wayne, Jeffrey; Wolff, Edward; Crane, Christopher; Pisters, Peter; Evans, Douglas (2015-11-10)
    Pancreatic adenocarcinoma is the fifth leading cause of cancer-related death in the U.S. In spite of advancements in surgical treatment, nearly 80% of patients thought to have localized pancreatic cancer die of recurrent ...
  • Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma 
    Katz, Matthew; Wang, Huamin; Fleming, Jason; Sun, Charlotte; Hwang, Rosa; Wolff, Robert; Varadhachary, Gauri; Abbruzzese, James; Crane, Christopher; Krishnan, Sunil; Vauthey, Jean-Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-17)
    Introduction Actual 5-year survival rates of 10–18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term ...
  • Pancreaticoduodenectomy with vascular resection 
    Abdalla, Eddie; Tseng, Jennifer; Raut, Chandrajit; Lee, Jeffrey; Pisters, Peter; Vauthey, Nicolas; Gomez, Henry; Sun, Charlotte; Crane, Christopher; Wolff, Robert; Evans, Douglas (2015-11-11)
    Major vascular resection performed at the time of pancreaticoduodenectomy (PD) for adenocarcinoma remains controversial. We analyzed all patients who underwent vascular resection (VR) at the time of PD for any histology ...
  • Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head 
    Varadhachary, Gauri; Wolff, Robert; Crane, Christopher; Sun, Charlotte; Lee, Jeffrey; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wang, Huamin; Staerkel, Gregg; Ross, William; Tamm, Eric; Bhosale, Priya; Krishnan, Sunil; Das, Prajnan; Ho, Linus; Xiong, Henry; Abbruzzese, James; Evans, Douglas (2015-11-17)
    Purpose We conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy (PD) for patients with stage I/II pancreatic adenocarci ...
  • Radiation treatment outcomes for unresectable hepatocellular carcinoma 
    Skinner, Heath; Sharp, Hadley; Kaseb, Ahmed; Javle, Milind; Vauthey, Jean-Nicolas; Abdalla, Eddie; Declos, Marc; Das, Prajnan; Crane, Christopher; Krishnan, Sunil (2015-11-20)
    Background. Hepatocellular carcinoma is one of the most common cancers worldwide. Data regarding the use of radiotherapy is limited in patients from populations without endemic viral hepatitis. We examine the outcomes for ...
  • Serum CA 19-9 as a Marker of Resectability and Survival in Patients with Potentially Resectable Pancreatic Cancer Treated with Neoadjuvant Chemoradiation 
    Katz, Matthew; Varadhachary, Gauri; Fleming, Jason; Wolff, Robert; Lee, Jeffrey; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Sun, Charlotte; Wang, Huamin; Crane, Christopher; Lee, Jeffrey; Tamm, Eric; Abbruzzese, James; Evans, Douglas (2015-11-19)
    Purpose The role of carbohydrate antigen (CA) 19-9 in the evaluation of patients with resectable pancreatic cancer treated with neoadjuvant therapy prior to planned surgical resection is unknown. We evaluated CA 19-9 as ...

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