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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Abdalla, Eddie"

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Browsing Gilbert and Rose-Marie Chagoury School of Medicine by Author "Abdalla, Eddie"

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  • Hepatic Insufficiency and Mortality in 1,059 Noncirrhotic Patients Undergoing Major Hepatectomy 
    Mullen, John; Ribero, Dario; Reddy, Srinevas; Donadon, Matteo; Zorzi, Daria; Gautam, Shiva; Abdalla, Eddie; Curley, Steven; Capussotti, Lorenzo; Clary, Bryan; Vauthey, Nicolas (2015-11-16)
    Background To establish a reliable definition of postoperative hepatic insufficiency (PHI) in noncirrhotic patients undergoing major hepatectomy. No standard definition of PHI has been established, but one is essential ...
  • Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases 
    Zalinski, Stephanie; Palavecino, Martin; Abdalla, Eddie (2015-11-19)
    Liver resection is the preferred treatment for gastrointestinal stromal tumor liver metastases (GIST LMs) when complete resection can be achieved. Major and extended hepatic resections can be safely performed, and using ...
  • Hepatic Resection for Metastatic Melanoma 
    Abdalla, Eddie; Pawlik, Timothy; Zorzi, Daria; Clary, Bryan; Gershenwald, Jeffrey; Ross, Merrick; Aloia, Thomas; Curley, Steven; Camacho, Luis; Capussotti, Lorenzo; Elias, Dominique; Vauthey, Nicolas (2015-11-12)
    Background Resection of melanoma metastatic to the liver remains controversial. We evaluated the efficacy of hepatic resection in patients with metastatic ocular and cutaneous melanoma and assessed factors that could ...
  • Hepatic vascular occlusion 
    Abdalla, Eddie; Noun, Roger; Belghiti, Jacques (2015-11-10)
  • Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma 
    Abdalla, Eddie; Pawlik, Timothy; Poon, Ronnie; Sarmiento, Juan; Lkai, Iwao; Curley, Steven; Nagorney, David; Belghiti, Jacques; Oi-Lin Ng, Irene; Yamaoka, Yoshio; Lauwers, Gregory; Vauthey, Nicolas (2015-11-10)
    The impact of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection on survival rates after resection of hepatocellular carcinoma (HCC) is controversial. The objective of this study was to determine whether serologic ...
  • High Survival Rate After Two-Stage Resection of Advanced Colorectal Liver Metastases 
    Brouquet, Antoine; Abdalla, Eddie; Kopetz, Scott; Garrett, Christopher; Overman, Micheal; Eng, Cathy; Andreou, Andreas; Loyer, Evelyne; Madoff, David; Curley, Steven; Vauthey, Jean-Nicolas (2015-11-19)
    Purpose Prolonged survival after two-stage resection (TSR) of advanced colorectal liver metastases (CLM) may be the result of selection of best responders to chemotherapy. The impact of complete resection in this well-selected ...
  • High-resolution computed tomography accurately predicts resectability in hilar cholangiocarcinoma 
    Aloia, Thomas; Chamsangavej, Chulsip; Faria, Silvana; Ribero, Dario; Abdalla, Eddie; Vauthey, Nicolas; Curley, Steven (2015-11-12)
    Introduction Despite the use of radiologic, endoscopic, and laparoscopic staging techniques, the rate of nontherapeutic laparotomies in patients with hilar cholangiocarcinoma remains high. This study evaluated the ...
  • I-CLIP 
    Kaseb, A.O.; Abbruzzese, J.L.; Vauthey, J.-N.; Aloia, T.A.; Abdalla, Eddie; Hassan, M.M.; Xiao, L.; Lin, E.; Rashid, A.; Morris, J.S. (2015-11-19)
    Objective: Improving the prognostic stratification of unresectable hepatocellular carcinoma (HCC) patients is critically needed. Since patients’ survival is closely linked to the severity of the underlying liver disease, ...
  • Identification of Cancer Stem Cells in Human Gastrointestinal Carcinoid and Neuroendocrine Tumors 
    Gaur, Puja; Sceusi, Eric; Samuel, Shaija; Xia, Ling; Zhou, Yunfei; Lu, Jia; Tozzi, Federico; Lopez-Berestein, Gabriel; Vivas-Mejia, Pablo; Fleming, Jason; Abdalla, Eddie; Curley, Steven; Vauthey, Jean-Nicolas; Sood, Anil; Yao, James; Ellis, Lee (2015-11-19)
    Background & Aims Metastatic gastrointestinal neuroendocrine tumors (NETs) frequently are refractory to chemotherapy. Chemoresistance in various malignancies has been attributed to cancer stem cells (CSCs). We sought ...
  • Impact of Resection Status on Pattern of Failure and Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma 
    Raut, Chandrajit; Tseng, Jennifer; Sun, Charlotte; Wang, Huamin; Wolff, Robert; Crane, Christopher; Vauthey, Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-16)
    Objective: To better understand the impact of a microscopically positive margin (R1) on patterns of disease recurrence and survival after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma. Summary Background ...
  • Improved Survival after Resection of Liver and Lung Colorectal Metastases Compared with Liver-Only Metastases 
    Brouquet, Antoine; Vauthey, Jean-Nicolas; Contreras, Carlo; Walsh, Garett; Vaporciyan, Ara; Swisher, Stephen; Curley, Steven; Mehran, Reza; Abdalla, Eddie (2017-04-11)
    Background Lung metastases are considered a poor prognostic factor in patients with resectable colorectal liver metastases. Study Design We reviewed records of 1,260 consecutive patients with liver-only or ...
  • Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha 
    Abdalla, Eddie; Moshyedi, Armin; Joseph, Michael; Mackay, Sally; Edwards III, Carl; Copeland III, Edward; Moldawer, Lyle (2015-11-09)
    Plasma leptin and ob gene mRNA levels were increased in mice following bacterial peritonitis, and blocking an endogenous tumor necrosis factor alpha (TNF-α) response blunted the increase. However, plasma leptin concentrations ...
  • Is embolization of segment 4 portal veins before extended right hepatectomy justified? 
    Kishi, Yoji; Madoff, David; Abdalla, Eddie; Palavecino, Martin; Ribero, Dario; Shin Chun, Yun; Vauthey, Jean-Nicolas (2015-11-17)
    Background Preoperative portal vein embolization (PVE) is increasingly used as a preparation for major hepatectomy in patients with inadequate liver remnant volume or function. However, whether segment 4 (S4) portal ...
  • Is extended hepatectomy for hepatobiliary malignancy justified? 
    Abdalla, Eddie; Vauthey, Nicolas; Pawlik, Timothy; Arens, James; Nemr, Rabih; Wei, Steven; Kennamer, Debra; Ellis, Lee; Curley, Steven (2015-11-11)
    Background: Extended hepatectomy may be required to provide the best chance for cure of hepatobiliary malignancies. However, the procedure may be associated with significant morbidity and mortality. Methods: We ...
  • Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified? 
    Brouquet, Antoine; Overman, Micheal; Kopetz, Scott; Maru, Dipen; Loyer, Evelyne; Andreou, Andreas; Cooper, Amanda; Curley, Steven; Garrett, Christopher; Abdalla, Eddie; Vauthey, Jean-Nicolas (2017-05-23)
    BACKGROUND: Patient outcomes following resection of colorectal liver metastases (CLM) after second-line chemotherapy regimen is unknown. METHODS: From August 1998 to June 2009, data from 1099 patients with CLM were ...
  • Laparoscopy for diagnosis and staging of hepatobiliary malignancies 
    Abdalla, Eddie; Aloia, Thomas; Vauthey, Nicolas (2015-11-11)
    Objective: To review the role of diagnostic laparoscopy (DL) for staging of malignant diseases of the liver and biliary tract. Methodology: Critical review of the current literature. Results: Analysis of the utility ...
  • Liver resection for liver metastases from nondigestive endocrine cancer 
    Andreou, Andreas; Brouquet, Antoine; Bharathy, Kishore; Perrier, Nancy; Abdalla, Eddie; Curley, Steven; Glanemann, Matthias; Seehofer, Daniel; Neuhaus, Peter; Vauthey, Jean-Nicolas; Aloia, Thomas (2015-11-20)
    Background For patients with hepatic nondigestive endocrine metastases (HNEM), the role of liver resection is not well-defined. Methods We reviewed outcomes for patients who underwent liver resection for HNEM at ...
  • Liver resection in the treatment of hepatocellular carcinoma 
    Abdalla, Eddie; Ribero, Dario; Thomas, Melanie; Vauthey, Nicolas (2015-11-12)
    Hepatocellular carcinoma is a leading cause of cancer death worldwide. Liver resection and liver transplantation remain the only options for cure. Since the indications for orthotopic liver transplantation are limited, ...
  • Liver-Directed Surgery for Metastatic Squamous Cell Carcinoma to the Liver 
    Pawlik, Timothy; Gleisner, Ana Luiza; Bauer, Todd; Reddy, Srinevas; Clary, Bryan; Martin, Robert; Scoggins, Charles; Tanabe, Kenneth; Michealson, James; Kooby, David; Staley, Charles; Schulick, Richard; Vauthey, Nicolas; Abdalla, Eddie; Curley, Steven; Choti, Micheal; Elias, Dominique (2015-11-16)
    Background The role of hepatic resection for metastatic squamous cell carcinoma (SCC) remains unknown. The current study evaluates the role of hepatic resection in patients with metastatic SCC to the liver. Methods Between ...
  • Localized adenocarcinoma of the pancreas: the rationale for preoperative chemoradiation 
    Abdalla, Eddie; Wayne, Jeffrey; Wolff, Edward; Crane, Christopher; Pisters, Peter; Evans, Douglas (2015-11-10)
    Pancreatic adenocarcinoma is the fifth leading cause of cancer-related death in the U.S. In spite of advancements in surgical treatment, nearly 80% of patients thought to have localized pancreatic cancer die of recurrent ...

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