.

Browsing School of Arts and Sciences by Author "Zalloua, Pierre A."

LAUR Repository

Browsing School of Arts and Sciences by Author "Zalloua, Pierre A."

Sort by: Order: Results:

  • ALOX5AP gene variants show differential association with coronary artery disease in different populations 
    Alwan, Ahmad; Youhanna, Sonia C.; Platt, Daniel E.; El-Sibai, Mirvat; Yerezian, Joumana S.; Deeb, Mary E.; Khazen, Georges; Saade, Stephanie; Zreik, Tony G.; El Bayeh, Hamid; Maalouf, Assaad; Zalloua, Pierre A.; Abchee, Antoine (2015-12-17)
    Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. Previous reports correlating ALOX5AP gene variants and CAD showed conflicting results depending on the population ...
  • Circulating lipid levels and risk of coronary artery disease in a large group of patients undergoing coronary angiography 
    Deeb, Mary E.; Khazen, Georges; Zalloua, Pierre A.; Platt, Daniel E.; Ghassibe-Sabbagh, Michella; Cazier, Jean-Baptiste; Kamatani, Yoichiro; Salloum, Angelique K.; Hager, Jo¨rg; Youhanna, Sonia (2016-11-23)
    A main underlying pathology of coronary artery disease is the deposition of cholesterol in the arteries supplying blood to the heart that leads to stenosis and myocardial infarction. We tested if dyslipidemia is a risk ...
  • Genome-Wide Association Study in a Lebanese Cohort Confirms PHACTR1 as a Major Determinant of Coronary Artery Stenosis 
    Hager, Jorg; Kamatani, Yoichiro; Cazier, Jean-Baptiste; Youhanna, Sonia; Ghassibe-Sabbagh, Michella; Platt, Daniel E.; Abchee, Antoine B.; Romanos, Jihane; Khazen, Georges; Othman, Raed; Badro, Danielle A.; Haber, Marc; Salloum, Angelique K.; Zalloua, Pierre A. (2016-03-17)
    The manifestation of coronary artery disease (CAD) follows a well-choreographed series of events that includes damage of arterial endothelial cells and deposition of lipids in the sub-endothelial layers. Genome-wide ...
  • Geographical Structure of the Y-chromosomal Genetic Landscape of the Levant 
    El-Sibai, Mirvat; Platt, Daniel E.; Haber, Marc; Xue, Yali; Youhanna, Sonia C.; Wells, R. Spencer; Izaabel, Hassan; Sanyoura, May F.; Harmanani, Haidar; Bonab, Maziar Ashrafian; Behbehani, Jaafar; Hashwa, Fuad; Tyler-Smith, Chris; Zalloua, Pierre A.; The Genographic Consortium (2015-11-04)
    We have examined the male-specific phylogeography of the Levant and its surroundings by analyzing Y-chromosomal haplogroup distributions using 5874 samples (885 new) from 23 countries. The diversity within some of these ...
  • The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease 
    Abchee, Antoine; El-Sibai, Mirvat; Youhanna, Sonia; Yeretzian, Joumana S.; Hanine, Estephan; Makhoul, Nadine J.; Puzantian, Houry; Sawaya, Jaber; Nasrallah, Antoine; Rebeiz, Abdallah G.; Zreik, Tony G.; Azar, Sami T.; Zalloua, Pierre A. (2017-07-27)
    Background: Mutations in genes regulating lipid metabolism, vasoactivity, and coagulation are important modulators of coronary artery disease (CAD). Objective: This study investigated the association between allelic ...
  • Influences of history, geography, and religion on genetic structure 
    Haber, Marc; Platt, Daniel E.; Badro, Danielle A.; Xue, Yali; El-Sibai, Mirvat; Bonab, Maziar Ashrafian; Youhanna, Sonia C.; Saade, Stephanie; Soria-Hernanz, David F.; Royyuru, Ajay; Wells, R. Spencer; Tyler-Smith, Chris; Zalloua, Pierre A. (2017-08-10)
    Cultural expansions, including of religions, frequently leave genetic traces of differentiation and in-migration. These expansions may be driven by complex doctrinal differentiation, together with major population migrations ...
  • Large scale association analysis identifies three susceptibility loci for coronary artery disease 
    El-Khazen, Georges; Zalloua, Pierre A.; Saade, Stephanie; Cazier, Jean-Baptiste; Ghassibe-Sabbagh, Michella; Youhanna, Sonia; Badro, Danielle A.; Kamatani, Yoichiro (2016-03-17)
    Genome wide association studies (GWAS) and their replications that have associated DNA variants with myocardial infarction (MI) and/or coronary artery disease (CAD) are predominantly based on populations of European or ...
  • Mapping post-glacial expansions 
    Khazen, Georges; Zalloua, Pierre A.; Platt, Daniel E.; Dagher- Kharrat, Magda Bou; Douaihy, Bouchra; Bonab, Maziar Ashrafian; Salloum, Angelique; Mouzaya, Francis; Luiselli, Donata; Tyler-Smith, Chris; Renfrew, Colin; Matisoo-Smith, Elizabeth (2017-04-25)
    Archaeological, palaeontological and geological evidence shows that post-glacial warming released human populations from their various climate-bound refugia. Yet specific connections between these refugia and the timing ...
  • Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population 
    Ghassibe-Sabbagh, Michella; Deeb, Mary; Saloum, Angelique K.; Hirbli, Kamal; Ahdab, Rechdi; Zalloua, Pierre A.; Nemr, Rita; Mouzaya, Francis; Chami, Youssef; Akle, Yasmine; Platt, Daniel E. (2016-06-14)
    Background: The burden of diabetes in Lebanon requires well-targeted interventions for screening type 2 diabetes mellitus (T2DM) and prediabetes and prevention of risk factors. Newly recruited 998 Lebanese individuals, ...
  • Phylogenetic assessment of heterotrophic bacteria from a water distribution system using 16S rDNA sequencing 
    Tokajian, Sima T.; Hashwa, Fuad A.; Zalloua, Pierre A.; Hancock, Ian C. (2016-03-23)
    Determination of a heterotrophic plate count (HPC) for drinking-water samples alone is not enough to assess possible health hazards associated with sudden changes in the bacterial count. Speciation is very crucial to ...
  • Plasma and urine metabolomic analyses in aortic valve stenosis reveal shared and biofluid-specific changes in metabolite levels 
    Al Hageh, Cynthia; Rahy, Ryan; Khazen, Georges; Brial, Francois; Khnayzer, Rony S.; Gauguier, Dominique; Zalloua, Pierre A. (2023-01-12)
    Aortic valve stenosis (AVS) is a prevalent condition among the elderly population that eventually requires aortic valve replacement. The lack of reliable biomarkers for AVS poses a challenge for its early diagnosis and the ...
  • Y-Chromosome and mtDNA Genetics Reveal Significant Contrasts in Affinities of Modern Middle Eastern Populations with European and African Populations 
    Khazen, Georges; Zalloua, Pierre A.; Badro, Danielle A.; Douaihy, Bouchra; Haber, Marc; Youhanna, Sonia C.; Salloum, Angélique; Ghassibe-Sabbagh, Michella; Johnsrud, Brian (2016-03-17)
    The Middle East was a funnel of human expansion out of Africa, a staging area for the Neolithic Agricultural Revolution, and the home to some of the earliest world empires. Post LGM expansions into the region and subsequent ...

Search LAUR


Advanced Search

Browse

My Account