El Maarri, Osman; Oldenburg, Johannes; Rost, Simone; Leuer, Marco; Olek, Klaus; Muller, Clemen R.; Schwaab, Rainer
(2017-09-12)
The intron 22 inversion represents the most prevalentfactor VIII gene defect in severe hemophilia A, accounting for about 40% of all mutations. It is hypothesized that the inversion mutations occur almost exclusively in ...