Diagnostic markers of postoperative morbidity after laparoscopic Roux-en-Y gastric bypass for obesity

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dc.contributor.author Romain, Benoît
dc.contributor.author Chemaly, Rodrigue
dc.contributor.author Meyer, Nicolas
dc.contributor.author Chilintseva, Natalia
dc.contributor.author Triki, Elhocine
dc.contributor.author Brigand, Cécile
dc.contributor.author Rohr, Serge
dc.date.accessioned 2022-11-04T14:18:12Z
dc.date.available 2022-11-04T14:18:12Z
dc.date.copyright 2014 en_US
dc.date.issued 2022-11-04
dc.identifier.issn 1435-2451 en_US
dc.identifier.uri http://hdl.handle.net/10725/14215
dc.description.abstract Purpose The main objective of this study was to detect subacute complications that can arise from laparoscopic Roux-en-Y gastric bypass and take a rational approach to manage these complications. Methods A prospective observational study was performed from November 2010 to December 2012. All patients undergoing gastric bypass surgery for morbid obesity were included in this study. Patients with complications before day 5 were excluded from the study. Clinical and laboratory data (C-reactive protein, leukocyte count) at postoperative day 5, 30-day morbidity, were recorded. The diagnostic value of C-reactive protein (CRP) and leukocytes were determined by the area under the curve (AUC) of the receiver operating characteristic (ROC) curve. Results One hundred and twenty-six patients were included. The overall incidence of 30-day morbidity was 8.7 %, and anastomotic leakage rate was 3.2 %. C-reactive protein at postoperative day 5 was a good predictor of complications (AUC was 0.862 (95 % CI [0.76; 0.96]; p < 0.001) and anastomotic leakage (AUC was 0.863 (95 % CI [0.66; 1]; p = 0.014). A CRP cutoff level of 136 mg/l at postoperative day 5 yielded a specificity of 95.5 % and a sensitivity of 57.1 % for the detection of postoperative complications. The negative predictive value was 94.6 %. A CRP level of 136 mg/l at day 5 was significantly associated with postoperative morbidity. Conclusions C-reactive protein dosage at postoperative day 5 is a relevant predictor of postoperative complications permitting to select patients at risk. Radiological examination and close monitoring could be restricted to patients with CRP level exceeding 136 mg/l. en_US
dc.language.iso en en_US
dc.title Diagnostic markers of postoperative morbidity after laparoscopic Roux-en-Y gastric bypass for obesity en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201805037 en_US
dc.author.department N/A en_US
dc.relation.journal Langenbeck's archives of surgery en_US
dc.journal.volume 399 en_US
dc.journal.issue 4 en_US
dc.article.pages 503-508 en_US
dc.keywords C-reactive protein en_US
dc.keywords Postoperative complications en_US
dc.keywords Gastric bypass en_US
dc.keywords Obesity surgery en_US
dc.identifier.doi https://doi.org/10.1007/s00423-014-1180-z en_US
dc.identifier.ctation Romain, B., Chemaly, R., Meyer, N., Chilintseva, N., Triki, E., Brigand, C., & Rohr, S. (2014). Diagnostic markers of postoperative morbidity after laparoscopic Roux-en-Y gastric bypass for obesity. Langenbeck's archives of surgery, 399(4), 503-508. en_US
dc.author.email rodrigue.chemaly@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://link.springer.com/article/10.1007/s00423-014-1180-z en_US
dc.orcid.id https://orcid.org/0000-0002-3670-6027 en_US
dc.author.affiliation Lebanese American University en_US

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