dc.contributor.author |
Khalil, Charbel |
|
dc.contributor.author |
Chaker, Diana |
|
dc.contributor.author |
Salameh, Rawad |
|
dc.contributor.author |
Germanos, Yvonne-Elise |
|
dc.contributor.author |
El Kayem, Elie |
|
dc.contributor.author |
Nader, Fady |
|
dc.contributor.author |
Habbouche, Jessica |
|
dc.contributor.author |
Chemaly, Rodrigue |
|
dc.contributor.author |
Azar, Albert |
|
dc.contributor.author |
Ibrahim, Ahmad |
|
dc.date.accessioned |
2022-11-02T11:17:34Z |
|
dc.date.available |
2022-11-02T11:17:34Z |
|
dc.date.copyright |
2021 |
en_US |
dc.date.issued |
2022-11-02 |
|
dc.identifier.issn |
2169-2513 |
en_US |
dc.identifier.uri |
http://hdl.handle.net/10725/14205 |
|
dc.description.abstract |
Context and Aim: Mesenchymal stem cells (MSCs) and platelet-rich fibrin (PRF) have emerged as ideal candidates for advanced therapies of various therapeutically-challenging diseases; however, their regenerative potential in diabetic foot ulcers (DFU) has not been well determined. In this study, we reviewed our clinical experience in mitigating chronic ulcer complications of diabetic foot through a conventional treatment of autologous adipose-derived MSCs embedded in PRF with pure PRF injections. Materials and Methods: The present study was carried out in 10 patients with an open DFU wound selected over a period of 1 year starting from April 2019. Patients were either injected with PRF alone (Group A) or injected with MSCs derived from adipose tissue (ADMSC) embedded in (PRF (Group B). Results: Patients in Group B had a better healing index when compared to Group A. Conclusion: Use of ADMSC embedded in PRF showed promising results to treat DFU. |
en_US |
dc.language.iso |
en |
en_US |
dc.title |
Autologous adipose-derived mesenchymal stem cells embedded in platelet-rich fibrin in diabetic foot ulcers |
en_US |
dc.type |
Article |
en_US |
dc.description.version |
Published |
en_US |
dc.author.school |
SOM |
en_US |
dc.author.idnumber |
201805037 |
en_US |
dc.author.department |
N/A |
en_US |
dc.relation.journal |
Open Journal of Regenerative Medicine |
en_US |
dc.journal.volume |
10 |
en_US |
dc.journal.issue |
2 |
en_US |
dc.article.pages |
19-30 |
en_US |
dc.keywords |
Diabetic Foot Ulcer |
en_US |
dc.keywords |
Diabetes |
en_US |
dc.keywords |
Mesenchymal Stem Cells |
en_US |
dc.keywords |
Adipose Tissue |
en_US |
dc.keywords |
Platelet Rich Fibrin |
en_US |
dc.identifier.doi |
https://doi.org/10.4236/ojrm.2021.102002 |
en_US |
dc.identifier.ctation |
Khalil, C., Chaker, D., Salameh, R., Germanos, Y. E., El Kayem, E., Nader, F., ... & Ibrahim, A. (2021). Autologous Adipose-Derived Mesenchymal Stem Cells Embedded in Platelet-Rich Fibrin in Diabetic Foot Ulcers. Open Journal of Regenerative Medicine, 10(2), 19-30. |
en_US |
dc.author.email |
rodrigue.chemaly@lau.edu.lb |
en_US |
dc.identifier.tou |
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php |
en_US |
dc.identifier.url |
https://www.scirp.org/journal/paperinformation.aspx?paperid=110795 |
en_US |
dc.orcid.id |
https://orcid.org/0000-0002-3670-6027 |
en_US |
dc.author.affiliation |
Lebanese American University |
en_US |