Gastroesophageal Cancer After Gastric Bypass Surgeries

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dc.contributor.author Chemaly, Rodrigue
dc.contributor.author Diab, Samer
dc.contributor.author Khazen, Georges
dc.contributor.author Al-Hajj, Georges
dc.date.accessioned 2022-11-01T13:39:31Z
dc.date.available 2022-11-01T13:39:31Z
dc.date.copyright 2022 en_US
dc.date.issued 2022-11-01
dc.identifier.issn 0960-8923 en_US
dc.identifier.uri http://hdl.handle.net/10725/14193
dc.description.abstract Data comparing the occurrence of gastroesophageal cancer after gastric bypass procedures are lacking and are only available in the form of case reports. We perform in this study a systematic review and a meta-analysis of all the reported cases of gastroesophageal cancer following Roux-en-Y gastric bypass (RYGB) and loop gastric bypass-one anastomosis gastric bypass/mini gastric bypass (LGB-OAGB/MGB). We conducted a systematic review of all the reported cases in articles referenced in PubMed/Medline, Cochrane, and Scholar Google. Only cases of gastro-esophageal adenocarcinoma following RYGB or LGB-OAGB/MGB are included. Statistical analysis was done accordingly. Fifty cases were identified, along with 2 reported in this paper. Sixty-one percent (27/44) of the cancers after RYGB were in the gastric tube compared to 37.5% (3/8) after LGB-OAGB/MGB. This resulted in an odds ratio of 0.38 (p-value = 0.26), which failed to prove an increase in cancer occurrence in the gastric tube after LGB-MGB/OAGB compared to RYGB. The most common symptoms were dysphagia for cancers occurring in the gastric tube (15/30) and abdominal pain for those occurring in the excluded stomach (10/22). Twenty-nine/thirty of the cancers in the gastric tube were diagnosed by gastroscopy and 13/22 of the cancers in the excluded stomach were diagnosed by CT scan. Gastroesophageal cancers after gastric bypass procedures occur commonly in the excluded stomach where many are not identified by conventional means. Physician awareness and patient education as well as lifelong follow-up are essential for maintaining bypass surgeries on the beneficial side. en_US
dc.language.iso en en_US
dc.title Gastroesophageal Cancer After Gastric Bypass Surgeries en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle a Systematic Review and Meta-analysis en_US
dc.author.school SOM en_US
dc.author.idnumber 201805037 en_US
dc.author.department N/A en_US
dc.relation.journal Obesity Surgery en_US
dc.journal.volume 32 en_US
dc.article.pages 1300–1311 en_US
dc.keywords Roux-en-y gastric bypass en_US
dc.keywords Mini gastric byass en_US
dc.keywords Gastric cancer en_US
dc.keywords Esophageal cancer en_US
dc.keywords Bariatric surgery en_US
dc.identifier.doi https://doi.org/10.1007/s11695-022-05921-4 en_US
dc.identifier.ctation Chemaly, R., Diab, S., Khazen, G., & Al-Hajj, G. (2022). Gastroesophageal Cancer After Gastric Bypass Surgeries: a Systematic Review and Meta-analysis. Obesity Surgery, 1300-1311. en_US
dc.author.email rodrigue.chemaly@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://link.springer.com/article/10.1007/s11695-022-05921-4 en_US
dc.orcid.id https://orcid.org/0000-0002-3670-6027 en_US
dc.author.affiliation Lebanese American University en_US

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