Retinal nerve fiber layer and macular thickness in amblyopia as measured by spectral domain optical coherence tomography

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dc.contributor.author Al-Haddad, Christiane E.
dc.contributor.author El Mollayess, Georges
dc.contributor.author Cherfan, Carol
dc.contributor.author Jaafar, Dalida
dc.contributor.author Bashshur, Ziad
dc.date.accessioned 2022-11-01T11:54:00Z
dc.date.available 2022-11-01T11:54:00Z
dc.date.copyright 2011 en_US
dc.date.issued 2022-11-01
dc.identifier.issn 0007-1161 en_US
dc.identifier.uri http://hdl.handle.net/10725/14184
dc.description.abstract Background/aims To study peripapillary retinal nerve fibre layer (RNFL) and macular thickness in amblyopia using high-definition spectral-domain optical coherence tomography (SD-OCT) and to compare the results with available literature using the time-domain modality. Methods This was a prospective institutional study of patients ≥6 years of age with unilateral amblyopia (strabismic or anisometropic) and non-amblyopic anisometropia. RNFL and macular thicknesses were measured using SD-OCT and compared between fellow eyes. Results The mean age was 20 (±12) years; 45 patients had amblyopia: 14 strabismic and 31 anisometropic. 20 patients had non-amblyopic anisometropia. The mean macular thickness was significantly increased in the amblyopic (273.8 μm) vs fellow eyes (257.9 μm), p=0.001. This difference remained significant in the anisometropic group (p=0.002) but not the strabismic group. The mean RNFL thickness was similar in amblyopic (95.4 μm) and fellow eyes (94.0 μm). Similar results were obtained regardless of the level of visual acuity, age or refractive error. In the control group of non-amblyopic anisometropia, the interocular difference did not reach statistical significance. Conclusions Central macular thickness was significantly increased in anisometropic amblyopia using SD-OCT. Anisometropia alone did not produce such a difference, which points to a possible correlation between amblyopia and the development of the retinal layers. en_US
dc.language.iso en en_US
dc.title Retinal nerve fiber layer and macular thickness in amblyopia as measured by spectral domain optical coherence tomography en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201805227 en_US
dc.author.department N/A en_US
dc.relation.journal British Journal of Ophthalmology (BJO) en_US
dc.journal.volume 95 en_US
dc.journal.issue 12 en_US
dc.article.pages 1696-1699 en_US
dc.identifier.doi http://dx.doi.org/10.1136/bjo.2010.195081 en_US
dc.identifier.ctation Al-Haddad, C. E., Mollayess, G. M., Cherfan, C. G., Jaafar, D. F., & Bashshur, Z. F. (2011). Retinal nerve fibre layer and macular thickness in amblyopia as measured by spectral-domain optical coherence tomography. British Journal of Ophthalmology, 95(12), 1696-1699. en_US
dc.author.email georges.elmollayess@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.proquest.com/docview/1778945816?fromopenview=true&pq-origsite=gscholar en_US
dc.author.affiliation Lebanese American University en_US

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