The role of corticosteroids in the early management of sepsis in the Lebanese population

Abstract

The use of corticosteroids in the management of sepsis has been quite controversial. This thesis was motivated by a pursuit to gain a better understanding about the safety and efficacy of using corticosteroids in sepsis. In order to achieve our objective, this thesis will capitalize on an intervention that has been previously implemented in a private hospital in Lebanon. The intervention entailed adding corticosteroids to the management protocol of a group of septic patients. Also to better understand the importance of this intervention, this thesis will specifically compare clinical outcomes of the group of patients who received the intervention (which took place between February 2018 and April 2019), to another group of septic patients admitted prior to the implementation of the intervention (patients admitted between January 2016 and February 2018). This study is in no way an interventional study, it will build on and analyze a previously conducted intervention in a retrospective manner.