Y-chromosomal diversity in Lebanon is structured by recent historical events

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dc.contributor.author Zalloua, Pierre A.
dc.contributor.author Xue, Yali
dc.contributor.author Khalife, Jade
dc.contributor.author Makhoul, Nadine
dc.contributor.author Debiane, Labib
dc.contributor.author Platt, Daniel E.
dc.contributor.author Royyuru, Aya K.
dc.contributor.author Herrera, Rene J.
dc.contributor.author Hernanz, David F. Soria
dc.contributor.author Blue-Smith, Jason
dc.contributor.author Wells, R. Spencer
dc.contributor.author Comas, David
dc.contributor.author Bertranpetit, Jaune
dc.contributor.author Tyler-Smith, Chris
dc.date.accessioned 2019-07-18T10:52:10Z
dc.date.available 2019-07-18T10:52:10Z
dc.date.copyright 2008 en_US
dc.date.issued 2019-07-18
dc.identifier.issn 1537-6605 en_US
dc.identifier.uri http://hdl.handle.net/10725/11084
dc.description.abstract Lebanon is an eastern Mediterranean country inhabited by approximately four million people with a wide variety of ethnicities and religions, including Muslim, Christian, and Druze. In the present study, 926 Lebanese men were typed with Y-chromosomal SNP and STR markers, and unusually, male genetic variation within Lebanon was found to be more strongly structured by religious affiliation than by geography. We therefore tested the hypothesis that migrations within historical times could have contributed to this situation. Y-haplogroup J∗(xJ2) was more frequent in the putative Muslim source region (the Arabian Peninsula) than in Lebanon, and it was also more frequent in Lebanese Muslims than in Lebanese non-Muslims. Conversely, haplogroup R1b was more frequent in the putative Christian source region (western Europe) than in Lebanon and was also more frequent in Lebanese Christians than in Lebanese non-Christians. The most common R1b STR-haplotype in Lebanese Christians was otherwise highly specific for western Europe and was unlikely to have reached its current frequency in Lebanese Christians without admixture. We therefore suggest that the Islamic expansion from the Arabian Peninsula beginning in the seventh century CE introduced lineages typical of this area into those who subsequently became Lebanese Muslims, whereas the Crusader activity in the 11th–13th centuries CE introduced western European lineages into Lebanese Christians. en_US
dc.language.iso en en_US
dc.title Y-chromosomal diversity in Lebanon is structured by recent historical events en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 20030001 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal American Journal of Human Genetics en_US
dc.journal.volume 82 en_US
dc.journal.issue 4 en_US
dc.article.pages 873-882 en_US
dc.identifier.doi https://doi.org/10.1016/j.ajhg.2008.01.020 en_US
dc.identifier.ctation Zalloua, P. A., Xue, Y., Khalife, J., Makhoul, N., Debiane, L., Platt, D. E., ... & Wells, R. S. (2008). Y-chromosomal diversity in Lebanon is structured by recent historical events. The American Journal of Human Genetics, 82(4), 873-882. en_US
dc.author.email pierre.zalloua@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.sciencedirect.com/science/article/pii/S0002929708002061 en_US
dc.orcid.id https://orcid.org/0000-0002-8494-5081 en_US
dc.author.affiliation Lebanese American University en_US

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