Hemodynamics of small aneurysm pairs at the internal carotid artery

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dc.contributor.author Jou, Liang-Der
dc.contributor.author Morsi, Hesham
dc.contributor.author Shaltoni, Hashem M.
dc.contributor.author Mawad, Michel E.
dc.date.accessioned 2019-07-10T11:14:10Z
dc.date.available 2019-07-10T11:14:10Z
dc.date.copyright 2012 en_US
dc.date.issued 2019-07-10
dc.identifier.issn 1873-4030 en_US
dc.identifier.uri http://hdl.handle.net/10725/11032
dc.description.abstract Cerebral aneurysms carry significant risks because rupture-related subarachnoid hemorrhage leads to serious and often fatal consequences. The rupture risk increases considerably for multiple aneurysms. Multiple aneurysms can grow from the same location of an artery, and the interaction between these aneurysms raises the rupture risk even higher. Four aneurysm pair cases at the internal carotid artery are investigated for their hemodynamic behaviors using patient-specific modeling. For each case, aneurysms are separated from the parent artery and three models are reconstructed, one with two aneurysms and the other two models with only one of the two aneurysms. Results show that the relative anatomic location of one aneurysm to the other may determine the hemodynamic environment of an aneurysm. The presence of a proximal aneurysm reduces the intra-aneurysmal flow into the distal aneurysm; the proximal aneurysm and larger aneurysm have a greater area under low wall shear stress. The average intra-aneurysmal inflow ratio ranges from 16% to 41%, and reduction of the inflow ratio by an aneurysm pair varies from 6% to 15%. The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk. en_US
dc.language.iso en en_US
dc.title Hemodynamics of small aneurysm pairs at the internal carotid artery en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201700518 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Medical Engineering & Physics en_US
dc.journal.volume 34 en_US
dc.journal.issue 10 en_US
dc.article.pages 1454-1461 en_US
dc.keywords Hemodynamics en_US
dc.keywords Wall shear stress en_US
dc.keywords Aneurysms en_US
dc.keywords Cerebrovascular disease en_US
dc.identifier.doi https://doi.org/10.1016/j.medengphy.2012.02.006 en_US
dc.identifier.ctation Jou, L. D., Morsi, H., Shaltoni, H. M., & Mawad, M. E. (2012). Hemodynamics of small aneurysm pairs at the internal carotid artery. Medical engineering & physics, 34(10), 1454-1461. en_US
dc.author.email michel.mawad@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.sciencedirect.com/science/article/pii/S1350453312000306 en_US
dc.author.affiliation Lebanese American University en_US

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