Cross-flow at the anterior communicating artery and its implication in cerebral aneurysm formation

LAUR Repository

Show simple item record

dc.contributor.author Jou, Liang-Der
dc.contributor.author Lee, Doek Hee
dc.contributor.author Mawad, Michel E.
dc.date.accessioned 2019-07-09T08:40:20Z
dc.date.available 2019-07-09T08:40:20Z
dc.date.copyright 2010 en_US
dc.date.issued 2019-07-09
dc.identifier.issn 1873-2380 en_US
dc.identifier.uri http://hdl.handle.net/10725/11010
dc.description.abstract The anterior communicating artery (ACoA) is an important element of the circle of Willis. While the artery itself is short and small, a large number of intracranial aneurysms can be found at the ACoA. Four subject-specific ACoA models are constructed from 3D rotational angiographic images. The ACoA of these models ranged from 1.7 to 2.7 mm in diameter and 1.5 to 5.7 mm in length. Pulsatile flows through these four ACoA models are studied numerically. Blood is found to move in two opposite directions simultaneously within the ACoA, giving a much higher wall shear at the ACoA. These two opposite flow streams produce a cross-flow that is dependent on the flow rates at the anterior cerebral arteries and internal carotid arteries (ICAs). A larger and shorter ACoA allows flow through the ACoA easily, leading to a greater cross-flow and higher hemodynamic forces on the artery. This cross-flow may disappear when there is a sufficient net flow for a smaller and longer ACoA. Wall shear stress can be as high as 185 Pa at smaller ACoAs, but it can be lowered by asymmetric waveforms at the ICAs. A functional circle of Willis also promotes cross-flow at both the ACoA and posterior communicating arteries. en_US
dc.language.iso en en_US
dc.title Cross-flow at the anterior communicating artery and its implication in cerebral aneurysm formation en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201700518 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Journal of Biomechanics en_US
dc.journal.volume 43 en_US
dc.journal.issue 11 en_US
dc.article.pages 2189-2195 en_US
dc.keywords Hemodynamics en_US
dc.keywords Cerebral aneurysm en_US
dc.keywords Circle of Willis en_US
dc.identifier.doi https://doi.org/10.1016/j.jbiomech.2010.03.039 en_US
dc.identifier.ctation Jou, L. D., Lee, D. H., & Mawad, M. E. (2010). Cross-flow at the anterior communicating artery and its implication in cerebral aneurysm formation. Journal of biomechanics, 43(11), 2189-2195. en_US
dc.author.email michel.mawad@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.sciencedirect.com/science/article/pii/S0021929010002010#aep-keywords-id13 en_US
dc.author.affiliation Lebanese American University en_US

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search LAUR

Advanced Search


My Account