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Incidence and clinical implications of carotid branch occlusion following treatment of internal carotid artery aneurysms with the pipeline embolization device

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dc.contributor.author Vedantam, Aditya
dc.contributor.author Rao, Vikas Y.
dc.contributor.author Shaltoni, Hashem M.
dc.contributor.author Mawad, Michel E.
dc.date.accessioned 2019-07-09T08:19:24Z
dc.date.available 2019-07-09T08:19:24Z
dc.date.copyright 2015 en_US
dc.identifier.issn 1524-4040 en_US
dc.identifier.uri http://hdl.handle.net/10725/11008
dc.description.abstract BACKGROUND: The use of flow diverters such as the pipeline embolization device (PED) for treatment of intracranial aneurysms carries the risk of side branch occlusion. OBJECTIVE: To determine the incidence and clinical outcomes associated with supraclinoid internal carotid artery (ICA) branch occlusion after deployment of PEDs for ICA aneurysms. METHODS: We reviewed patients who underwent endovascular treatment with PEDs for ICA aneurysms between June 2011 and March 2013. Forty-nine patients (43 women, mean age 56.3 ± 1.8 years, 68 aneurysms) in whom PEDs traversed the origin of supraclinoid ICA branches (ophthalmic [OA], posterior communicating [PcommA], and anterior choroidal artery [AChA]) were selected for this study. Follow-up angiograms (mean follow-up, 12.8 ± 0.8 months) were studied to determine the location of PEDs and the patency of ICA branches. RESULTS: PEDs were placed across the ostia of 49 OAs, 14 PcommAs, and 11 AChAs. Multiple PEDs were deployed in 16 patients. Rate of branch occlusion was 4% (2/49) for the OA, 7.1% (1/14) for the PcommA, and 0% for the AChA. Patients with branch occlusion did not endure new neurological deficits. ICA branch occlusion was not associated with the number of PEDs covering the ostia (P = .76) or the origin of ICA branches from the aneurysm (P = .24). CONCLUSION: The incidence of major supraclinoid ICA branch occlusion after treatment with PEDs was low. These events were not associated with new neurological deficits nor were they related to the number of PEDs deployed or the origin of ICA branches from the aneurysm. en_US
dc.language.iso en en_US
dc.title Incidence and clinical implications of carotid branch occlusion following treatment of internal carotid artery aneurysms with the pipeline embolization device en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201700518 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Neurosurgery en_US
dc.journal.volume 76 en_US
dc.journal.issue 2 en_US
dc.article.pages 173-178 en_US
dc.keywords Flow diverter en_US
dc.keywords Internal carotid artery aneurysm en_US
dc.keywords Pipeline embolization device en_US
dc.keywords Side branch occlusion en_US
dc.keywords Supraclinoid internal carotid artery en_US
dc.identifier.doi https://doi.org/10.1227/NEU.0000000000000595 en_US
dc.identifier.ctation Vedantam, A., Rao, V. Y., Shaltoni, H. M., & Mawad, M. E. (2014). Incidence and clinical implications of carotid branch occlusion following treatment of internal carotid artery aneurysms with the pipeline embolization device. Neurosurgery, 76(2), 173-178. en_US
dc.author.email michel.mawad@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://academic.oup.com/neurosurgery/article/76/2/173/2452153 en_US
dc.author.affiliation Lebanese American University en_US


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