Fluorescein angiography versus superimposed OCT-guided macular laser photocoagulation

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dc.contributor.author Kozak, Igor
dc.contributor.author El-Emam, Sharif
dc.contributor.author Cheng, Lingyun
dc.contributor.author Bartsch, Dirk-Uwe
dc.contributor.author Chhablani, Jay
dc.contributor.author Freeman, William
dc.contributor.author Ghazi, Nicola
dc.contributor.author Arevalo, J.Fernando
dc.date.accessioned 2019-06-21T09:50:18Z
dc.date.available 2019-06-21T09:50:18Z
dc.date.copyright 2013 en_US
dc.identifier.issn 1552-5783 en_US
dc.identifier.uri http://hdl.handle.net/10725/10892
dc.description.abstract Purpose: To compare diabetic macular edema (DME) laser treatment plans using fluorescein angiography (FA) versus optical coherence tomography (OCT) template superimposed on the retinal image. We hypothesize that information from integrated OCT retinal thickness map aligned onto fundus image will have an impact on treatment plan for these patients. Methods: Eight eyes of five patients with DME undergoing laser photocoagulation with navigated photocoagulator NAVILAS® (OD-OS, Inc., Berlin, Germany) had FA and OCT imaging done before treatment. FA image was taken with the same instrument and superimposed onto color fundus photo. OCT retinal thickness map taken on the Heidelberg Spectralis system (Heidelberg Engineering, Vista, CA) was imported to the laser photocoagulator unit and superimposed and aligned onto fundus image of the same magnification off line. The treatment plans for each eye consisted of placing laser spot marks separately on FA and OCT image in a masked fashion. The number of spots placed by physician was compared between FA and OCT using matched pairs analysis. The area of dye leakage on FA and increased retinal thickness on OCT on the same eye was measured using Heidelberg Explorer software. Results: Three masked retina specialists created treatment plans. The average number of planed spots using FA and OCT template was 36.67 and 42.20, respectively (p=0.0015). The average area of dye leakage on FA was 7.45 mm2 whereas the average area of increased retinal thickness on OCT superimposed on fundus image of the same eye was 10.92 mm2 (p=0.013). Conclusions: In eyes with DME the area of retinal thickening appears to be larger on OCT image than the area of dye leakage on FA templates. Physicians had a tendency to place more laser spots when guided by OCT than FA. Integration of OCT map aligned to retina may have an impact on treatment plan once this alignment takes place and such information is available. en_US
dc.language.iso en en_US
dc.title Fluorescein angiography versus superimposed OCT-guided macular laser photocoagulation en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Investigative Ophthalmology & Visual Science en_US
dc.journal.volume 54 en_US
dc.journal.issue 15 en_US
dc.article.pages 4133 en_US
dc.identifier.ctation Kozak, I., El-Emam, S., Cheng, L., Bartsch, D. U., Chhablani, J., Freeman, W., ... & Arevalo, J. F. (2013). Fluorescein angiography versus superimposed OCT-guided macular laser photocoagulation. Investigative Ophthalmology & Visual Science, 54(15), 4133-4133. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://iovs.arvojournals.org/article.aspx?articleid=2148962 en_US
dc.author.affiliation Lebanese American University en_US

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