Spectral-domain optical coherence tomography parameters associated with baseline vision in diabetic cystoid macular edema

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dc.contributor.author Alfaran, Abdulrahman
dc.contributor.author Mousa, Ahmed
dc.contributor.author Ghazi, Nicola
dc.date.accessioned 2019-06-21T09:43:10Z
dc.date.available 2019-06-21T09:43:10Z
dc.date.copyright 2013 en_US
dc.date.issued 2019-06-21
dc.identifier.issn 1552-5783 en_US
dc.identifier.uri http://hdl.handle.net/10725/10891
dc.description.abstract Purpose to study spectral-domain optical coherence tomography (SD-OCT) parameters that may be associated with baseline visual acuity in eyes with center-involved diabetic cystoid macular edema (DCME) Methods The analysis included eyes with new onset center-involved DCME that had to have had a macular SD-OCT and fluorescein angiography (FA) at presentation. The baseline OCT scans were analyzed for the extent of retinal involvement by the cystoid change and its location with respect to the center. Both inner and outer retinal parameters were assessed. Eyes with clinical and angiographic evidence of lipid and ischemic maculopathy and those with poor quality OCT were excluded. Statistical analysis correlating the various OCT variables with baseline logMAR visual acuity was performed. Results Forty-nine eyes of 35 patients were analyzed. Twenty-five patients (71.4%) were males and 10 (28.6%) were females with a mean (±SD) age of 57.22 (±10.4) years (range 29 - 78 years). The baseline Log MAR visual acuity, central macular thickness (CMT) and central foveal thickness (CFT) ranged from 0.3 to 1.2; mean (±SD) = 0.53 (±0.23) (20/40 to 20/300 Snellen equivalent range), 315 to 738 microns; mean (±SD) = 462.3 (±106.1) microns and 153 to 735 microns; mean (±SD) = 442.3 (±137.5) microns respectively. Pearson correlation test showed that the only OCT parameters associated with the baseline visual acuity were the chord length of involvement of the photoreceptor IS/OS junction within the central subfield (CSF) (p=0.001), the thickness of the residual photoreceptor outer segments within the CSF (p=0.002), and the size of the largest cystoid space within the CSF (p=0.037). Conclusions In DCME, baseline visual acuity appears to correlate strongly with the status of the photoreceptor outer segments and to a lesser extent with the degree of cystoid change in the CSF. These findings may help explain the impact of specific morphological changes on visual acuity in eyes with center-involved DCME en_US
dc.language.iso en en_US
dc.title Spectral-domain optical coherence tomography parameters associated with baseline vision in diabetic cystoid macular edema en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Investigative Ophthalmology & Visual Science en_US
dc.journal.volume 54 en_US
dc.journal.issue 15 en_US
dc.article.pages 2370 en_US
dc.identifier.ctation Alfaran, A., Mousa, A., & Ghazi, N. (2013). Spectral-Domain Optical Coherence Tomography Parameters Associated with Baseline Vision in Diabetic Cystoid Macular Edema. Investigative Ophthalmology & Visual Science, 54(15), 2370-2370. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://iovs.arvojournals.org/article.aspx?articleid=2147056 en_US
dc.author.affiliation Lebanese American University en_US

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