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Intravitreal bevacizumab injections can release vitreomacular adhesions in eyes with persistent diabetic macular edema and vitreomacular adhesions

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dc.contributor.author Al Judaibi, Ramzi M.
dc.contributor.author Al Shamsi, Hanan
dc.contributor.author Ghazi, Nicola G.
dc.date.accessioned 2019-06-21T06:44:08Z
dc.date.available 2019-06-21T06:44:08Z
dc.date.copyright 2012 en_US
dc.identifier.issn 1552-5783 en_US
dc.identifier.uri http://hdl.handle.net/10725/10879
dc.description.abstract Purpose: to report cases of persistent diabetic macular edema (DME) with vitreomacular adhesions (VMA) that responded to intravitreal bevacizumab (IVB) injection with separation of the VMA and complete or significant resolution of DME Methods: Three eyes of three patients were diagnosed with persistent DME and VMA following focal laser therapy based on typical clinical, angiographic, and spectral-domain optical coherence tomography (SD-OCT, Spectralis, Heidelberg, Germany) findings. A trial of IVB was attempted prior to proceeding with pars plana vitrectomy (PPV) to address the VMA. Results: All eyes disclosed cystoid macular edema with perifoveal vitreous separation and focal adhesion of the posterior hyaloid at the fovea on SD-OCT. Following one to three injections of IVB, SD-OCT showed complete separation of the VMA in all eyes with complete or significant resolution of the intraretinal fluid. Conclusions: Our findings suggest that a trial of intravitreal therapy, such as IVB, should be attempted in eyes with persistent DME and focal VMA before proceeding to PPV. The mechanical effect of the intravitreal injections may lead to separation of the VMA. This, together with the pharmacological effect of the injected agent, may lead to resolution of the DME as seen in the cases reported herein. en_US
dc.language.iso en en_US
dc.title Intravitreal bevacizumab injections can release vitreomacular adhesions in eyes with persistent diabetic macular edema and vitreomacular adhesions en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Investigative Ophthalmology & Visual Science en_US
dc.journal.volume 53 en_US
dc.journal.issue 14 en_US
dc.article.pages 416 en_US
dc.keywords Retinal adhesion en_US
dc.keywords Diabetic retinopathy en_US
dc.keywords Edema en_US
dc.identifier.ctation Al Judaibi, R. M., Al Shamsi, H., & Ghazi, N. G. (2012). Intravitreal Bevacizumab Injections can Release Vitreomacular Adhesions in Eyes with Persistent Diabetic Macular Edema and Vitreomacular Adhesions. Investigative Ophthalmology & Visual Science, 53(14), 416-416. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://iovs.arvojournals.org/article.aspx?articleid=2349233 en_US
dc.author.affiliation Lebanese American University en_US


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