Effect of intravitreal triamcinolone in advanced coats disease

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dc.contributor.author Ghazi, Nicola G.
dc.contributor.author Al Shamsi, Hanan
dc.contributor.author Larsson, Jorgen
dc.date.accessioned 2019-06-21T06:09:08Z
dc.date.available 2019-06-21T06:09:08Z
dc.date.copyright 2011 en_US
dc.identifier.issn 1552-5783 en_US
dc.identifier.uri http://hdl.handle.net/10725/10877
dc.description.abstract Purpose: : To report our experience with intravitreal triamcinolone (IVTA) in cases of advanced Coats disease with massive subretinal exudation (MSRE) Methods: : Two eyes of two cases of advanced Coats disease, one eye with stage 4 disease and one with stage 5, received IVTA. One eye received 1mg and one received 4mg IVTA. Because of the age and the limited space between the lens and the remaining vitreous cavity, the injections were performed under general anesthesia with ultrasound guidance. Results: : Both eyes had MSRE with total bullous retinal detachment that was almost touching the crystalline lens. One eye had neovascular glaucoma. IVTA was associated with almost total resolution of the subretinal fluid within 4 weeks from the injection. Subsequent application of ablative therapy without the need for surgical drainage was successfully performed on both eyes. None of the patients developed side effects from the treatment. Conclusions: : Our findings suggest that IVTA may be an effective alternative to surgical drainage in advanced cases of Coats disease. To our knowledge, 1mg of IVTA has not been previously reported in this setting. Larger prospective studies to address the dose, safety and efficacy of IVTA in the management of advanced Coats disease are needed. en_US
dc.language.iso en en_US
dc.title Effect of intravitreal triamcinolone in advanced coats disease en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle observations in two cases with stages 4 and 5 disease en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Investigative Ophthalmology & Visual Science en_US
dc.journal.volume 52 en_US
dc.journal.issue 14 en_US
dc.keywords Retinal detachment en_US
dc.keywords Retina en_US
dc.keywords clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials en_US
dc.identifier.ctation Ghazi, N. G., Al Shamsi, H., & Larsson, J. (2011). Effect of Intravitreal Triamcinolone in Advanced Coats Disease: Observations in Two Cases with Stages 4 and 5 Disease. Investigative Ophthalmology & Visual Science, 52(14), 6155-6155. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://iovs.arvojournals.org/article.aspx?articleid=2361970 en_US
dc.author.affiliation Lebanese American University en_US

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