Spectral-domain optical coherence tomography findings in polypoidal choroidal vasculopathy

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dc.contributor.author Ghazi, Nicola G.
dc.contributor.author Al Shamsi, Hanan
dc.contributor.author Al Kahtani, Eman
dc.date.accessioned 2019-06-20T11:54:28Z
dc.date.available 2019-06-20T11:54:28Z
dc.date.copyright 2012 en_US
dc.date.issued 2019-06-20
dc.identifier.issn 1552-5783 en_US
dc.identifier.uri http://hdl.handle.net/10725/10876
dc.description.abstract Purpose: to report spectral domain optical coherence tomography (SD-OCT) findings in polypoidal choroidal vasculopathy (PCV) Methods: Ten eyes of 10 consecutive patients were diagnosed with PCV based on typical clinical and angiographic findings including indocyanine green angiography. All eyes were also imaged with macular SD-OCT including line scans passing through the polyps. Results: SD-OCT findings included typical and atypical retinal pigment epithelial (RPE) detachments (PED) and subretinal and intraretinal fluid in all eyes. In addition in the areas corresponding to the polyps, well-delineated round-oval, sub-RPE cavities with low to medium reflectivity centrally and hyperreflective borders were noted within the space of an atypical PED. The cavities were adherent to the posterior surface of the detached RPE way above the subjacent Bruch membrane, and the RPE appeared to be draped over them. No retinal or choroidal connections to the cavities were noted. Conclusions: These findings suggest that the polyps in PCV are not located in the inner choroid, but rather in the sub-RPE space, anterior to Bruch membrane. The close proximity of the polyps to the RPE and the configuration of the RPE around the polyps may shed light on the pathogenesis of PCV and may also contribute to the relatively good prognosis of PCV compared to typical choroidal neovascularization. en_US
dc.language.iso en en_US
dc.title Spectral-domain optical coherence tomography findings in polypoidal choroidal vasculopathy en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle the polyps are anterior to bruch membrane en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Investigative ophthalmology and visual science en_US
dc.journal.volume 53 en_US
dc.journal.issue 14 en_US
dc.article.pages 1168 en_US
dc.keywords Imaging/image analysis: clinical en_US
dc.keywords Age-related macular degeneration en_US
dc.keywords Choroid: neovascularization en_US
dc.identifier.ctation Ghazi, N. G., Al Shamsi, H., & Al Kahtani, E. (2012). Spectral-Domain Optical Coherence Tomography Findings in Polypoidal Choroidal Vasculopathy: The Polyps are Anterior to Bruch Membrane. Investigative Ophthalmology & Visual Science, 53(14), 1168-1168. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://iovs.arvojournals.org/article.aspx?articleid=2350554 en_US
dc.author.affiliation Lebanese American University en_US

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