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Combined nonmydriatic spectral-domain optical coherence tomography and nonmydriatic fundus photography for the detection of age-related macular degeneration changes

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dc.contributor.author Salti, Haytham I.
dc.contributor.author Antonios, Rafic S.
dc.contributor.author Haddad, Sandra S.
dc.contributor.author Hamam, Rola N.
dc.contributor.author Bashshur, Ziad F.
dc.contributor.author Ghazi, Nicola G.
dc.date.accessioned 2019-06-19T09:33:32Z
dc.date.available 2019-06-19T09:33:32Z
dc.date.copyright 2015 en_US
dc.identifier.issn 2325-8179 en_US
dc.identifier.uri http://hdl.handle.net/10725/10863
dc.description.abstract BACKGROUND AND OBJECTIVE: Nonmydriatic fundus photography (FP) has been a suboptimal tool for detecting age-related macular degeneration (AMD) changes. This study sought to enhance the detection of AMD changes by combining nonmydriatic FP with nonmydriatic spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: The study population included 249 patients aged 65 years and older who were assessed for AMD changes using standard mydriatic biomicroscopic fundus examination. Each eye then underwent nonmydriatic FP in one session followed 1 week later with nonmydriatic FP coupled with nonmydriatic SD-OCT. Images were interpreted for detection of AMD changes, and findings were compared to the original mydriatic biomicroscopic examination. RESULTS: Nonmydriatic FP had 64% sensitivity, 97% specificity, and a kappa value of 0.67 in detecting AMD changes compared with the traditional mydriatic biomicroscopic examination. Combined nonmydriatic FP and nonmydriatic SD-OCT increased sensitivity to 91.5%, specificity to 98.6%, and kappa to 0.91. CONCLUSION: The addition of nonmydriatic SD-OCT to nonmydriatic FP enhances the detection of AMD changes. en_US
dc.language.iso en en_US
dc.title Combined nonmydriatic spectral-domain optical coherence tomography and nonmydriatic fundus photography for the detection of age-related macular degeneration changes en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Ophthalmic Surgery, Lasers and Imaging Retina en_US
dc.journal.volume 46 en_US
dc.journal.issue 5 en_US
dc.article.pages 531-537 en_US
dc.identifier.doi https://doi.org/10.3928/23258160-20150521-04 en_US
dc.identifier.ctation Salti, H. I., Antonios, R. S., Haddad, S. S., Hamam, R. N., Bashshur, Z. F., & Ghazi, N. G. (2015). Combined nonmydriatic spectral-domain optical coherence tomography and nonmydriatic fundus photography for the detection of age-related macular degeneration changes. Ophthalmic Surgery, Lasers and Imaging Retina, 46(5), 531-537. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.healio.com/ophthalmology/journals/osli/2015-5-46-5/%7B6ecc5721-015f-4082-963d-6d9f675e2abf%7D/combined-nonmydriatic-spectral-domain-optical-coherence-tomography-and-nonmydriatic-fundus-photography-for-the-detection-of-age-related-macular-degeneration-changes en_US
dc.author.affiliation Lebanese American University en_US


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