Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia

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dc.contributor.author Alshahrani, Saeed T.
dc.contributor.author Ghazi, Nicola G.
dc.contributor.author Al-Rashaed, Saba
dc.date.accessioned 2019-06-14T11:36:23Z
dc.date.available 2019-06-14T11:36:23Z
dc.date.copyright 2016 en_US
dc.date.issued 2019-06-14
dc.identifier.issn 1177-5483 en_US
dc.identifier.uri http://hdl.handle.net/10725/10831
dc.description.abstract Purpose To investigate the clinical findings and outcomes of rhegmatogenous retinal detachment (RRD) in Stickler syndrome on affected and fellow eyes that underwent prophylactic retinopexy. Patients and methods Chart review of 70 eyes (62 patients). Incidence of RRD, postoperative visual acuity, and risk factors were evaluated. Results Twenty-two patients (35%) had RRD in the fellow eye, 37% of the eyes had cataract, 93% had macular detachment, 50% had proliferative vitreoretinopathy, and 41% had posterior vitreous detachment. Success rates were: 60% of patients after scleral buckling; 57.1% after pars plana vitrectomy; and 75% after combined scleral buckling and pars plana vitrectomy. Sixty-one (93.8%) of patients had successful surgery (including second surgery). Silicone oil tamponade was significantly associated with final anatomic outcome, with a protective odds ratio of 0.11 (P=0.027). Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P<0.001); preoperative cataract (P=0.023); and proliferative vitreoretinopathy (P<0.001). RRD developed in 16/44 eyes despite laser prophylaxis. Conclusion Prophylactic retinopexy was not beneficial for Stickler syndrome patients. Success of primary surgery for RRD remains low. The primary surgery should be vitrectomy combined with scleral buckling and silicone oil tamponade en_US
dc.language.iso en en_US
dc.title Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Clinical Ophthalmology en_US
dc.journal.volume 10 en_US
dc.keywords Stickler syndrome en_US
dc.keywords Retinopexy en_US
dc.keywords Gulf States en_US
dc.keywords Saudi Arabia en_US
dc.keywords Ocular genetics en_US
dc.keywords Arthro-ophthalmopathy en_US
dc.keywords Collagen disorder en_US
dc.identifier.doi https://doi.org/10.2147/OPTH.S91444 en_US
dc.identifier.ctation Alshahrani, S. T., Ghazi, N. G., & Al-Rashaed, S. (2016). Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia. Clinical ophthalmology (Auckland, NZ), 10, 1. en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697790/ en_US
dc.author.affiliation Lebanese American University en_US

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