Impact of AREDS in a developing country 5 years after publication of the study

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dc.contributor.author Fahed, Daoud C.
dc.contributor.author Ghazi, Nicola G.
dc.contributor.author Jabbour, Nabil M.
dc.contributor.author Fahed, Charbel D.
dc.contributor.author Fahed, Chabel D.
dc.contributor.author Haytham, Salti I.
dc.date.accessioned 2019-06-14T10:03:59Z
dc.date.available 2019-06-14T10:03:59Z
dc.date.copyright 2011 en_US
dc.date.issued 2019-06-14
dc.identifier.issn 1724-6016 en_US
dc.identifier.uri http://hdl.handle.net/10725/10820
dc.description.abstract Purpose The Age-Related Eye Disease Study (AREDS) is the only large-scale study to demonstrate a reduction in the risk of progression to end-stage age-related macular degeneration (AMD) when vitamin supplementation was given to patients with advanced forms of the disease. Our study assesses the impact of this study on vitamin supplementation in patients with advanced AMD from 5 years before publication of the AREDS results until 5 years after. Methods Medical records of patients with AMD presenting between September 1996 and October 2006 were reviewed. Patients were subclassified according to AREDS categories. The proportion of advanced cases on vitamin replacement before October 2001 was compared to that after October 2001. Since October 2001, the different reasons for abstinence were investigated and analyzed. Results Only 2403 patients of the 40,000 medical records reviewed met the AREDS AMD criteria. Of these, 137 patients verifying categories 3 and 4 were diagnosed prior to October 2001. Fourteen were on supplements then. Fifty-three patients complied with the represcribed vitamins during subsequent visits after October 2001, raising the percentage significantly to 48.9% (p<0.001). Also, from October 2001 until October 2006, an additional 76 patients verified categories 3 and 4. Fifty-three (69.7%) of them were on vitamins (p=0.001). Financial burden was the principal reason for abstinence in 67.7% of patients prescribed vitamins after October 2001. Conclusions The results of AREDS had an impressive impact on prescribing supplements in AREDS category 3 and 4 patients in Lebanon. The main reason for noncompliance is financial. en_US
dc.language.iso en en_US
dc.title Impact of AREDS in a developing country 5 years after publication of the study en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 201000154 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal European Journal of Ophthalmology en_US
dc.journal.volume 21 en_US
dc.journal.issue 1 en_US
dc.article.pages 67-72 en_US
dc.keywords Age-related macular degeneration en_US
dc.keywords AREDS en_US
dc.keywords Developing country en_US
dc.keywords Vitamin supplement en_US
dc.identifier.doi https://doi.org/10.5301/EJO.2010.4138 en_US
dc.author.email nicola.ghazi@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://journals.sagepub.com/doi/abs/10.5301/EJO.2010.4138 en_US
dc.author.affiliation Lebanese American University en_US

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