Etiology of end-stage renal disease and arterial stiffness among hemodialysis patients

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dc.contributor.author El Ghoul, Balsam
dc.contributor.author Daaboul, Yazan
dc.contributor.author Korjian, Serge
dc.contributor.author El Alam, Andrew
dc.contributor.author Mansour, Anthony
dc.contributor.author Hariri, Essa
dc.contributor.author Samad, Salam
dc.contributor.author Salameh, Pascale
dc.contributor.author Dahdah, Georges
dc.contributor.author Blacher, Jacques
dc.contributor.author Safar, Michel E.
dc.contributor.author Bahous, Sola Aoun
dc.date.accessioned 2019-06-11T06:28:42Z
dc.date.available 2019-06-11T06:28:42Z
dc.date.copyright 2017 en_US
dc.date.issued 2019-06-11
dc.identifier.issn 2314-6141 en_US
dc.identifier.uri http://hdl.handle.net/10725/10770
dc.description.abstract Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness among a cohort of hemodialysis patients. Methods. Etiology of ESRD was identified from patients’ medical records and classified as either vascular renal disease, diabetic nephropathy, nondiabetic glomerulopathy, tubular interstitial nephropathy, hereditary nephropathy, or ESRD of unconfirmed etiology. Results. A total of 82 subjects were enrolled. cfPWV was independently associated with the composite of either diabetic nephropathy or vascular renal disease (p = 0.022), pulse pressure (p = 0.001), and a history of CV events (p = 0.025), but not history of hypertension or diabetes mellitus alone. The median cfPWVs in diabetic nephropathy and vascular renal disease were comparable and significantly higher than median cfPWVs in other etiologies of ESRD. Conclusion. The study suggests that the etiology of ESRD is independently associated with arterial stiffness among hemodialysis patients. Furthermore, arterial stiffness was higher among patients who developed renal sequelae of either diabetes mellitus or hypertension as compared with those who have a history of either diabetes mellitus or hypertension alone. en_US
dc.language.iso en en_US
dc.title Etiology of end-stage renal disease and arterial stiffness among hemodialysis patients en_US
dc.type Article en_US
dc.description.version Published en_US
dc.author.school SOM en_US
dc.author.idnumber 200803754 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal BioMed Research International en_US
dc.journal.volume 2017 en_US
dc.identifier.doi https://doi.org/10.1155/2017/2543262 en_US
dc.identifier.ctation El Ghoul, B., Daaboul, Y., Korjian, S., El Alam, A., Mansour, A., Hariri, E., ... & Safar, M. E. (2017). Etiology of end-stage renal disease and arterial stiffness among hemodialysis patients. BioMed research international, 2017. en_US
dc.author.email sola.bahous@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.hindawi.com/journals/bmri/2017/2543262/abs/ en_US
dc.orcid.id https://orcid.org/0000-0002-7159-7559 en_US
dc.author.affiliation Lebanese American University en_US

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