| dc.contributor.author |
Nemr, Rita |
|
| dc.contributor.author |
Turki, Amira |
|
| dc.contributor.author |
Echtay, Akram |
|
| dc.contributor.author |
Al-Zaben, Ghadeer S. |
|
| dc.contributor.author |
Daher, Hoda S. |
|
| dc.contributor.author |
Irani-Hakime, Nora A. |
|
| dc.contributor.author |
Kelestian, Sose H. |
|
| dc.contributor.author |
Almawi, Wassim Y. |
|
| dc.date.accessioned |
2019-05-29T09:05:08Z |
|
| dc.date.available |
2019-05-29T09:05:08Z |
|
| dc.date.copyright |
2012 |
en_US |
| dc.date.issued |
2019-05-29 |
|
| dc.identifier.issn |
1872-8227 |
en_US |
| dc.identifier.uri |
http://hdl.handle.net/10725/10694 |
|
| dc.description.abstract |
We tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695–rs4506565–rs7903146–rs12243326–rs7895340–rs11196205–rs12255372) identified positively- (2122112, 2222222) and negatively- (1111111) T2DM-associated haplotypes. TCF7L2 is a common T2DM candidate gene in Lebanese people. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.title |
Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects |
en_US |
| dc.type |
Article |
en_US |
| dc.description.version |
Published |
en_US |
| dc.author.school |
SOM |
en_US |
| dc.author.idnumber |
201004815 |
en_US |
| dc.author.department |
N/A |
en_US |
| dc.description.embargo |
N/A |
en_US |
| dc.relation.journal |
Diabetes Research and Clinical Practice |
en_US |
| dc.journal.volume |
98 |
en_US |
| dc.journal.issue |
3 |
en_US |
| dc.article.pages |
e23-e27 |
en_US |
| dc.keywords |
Diabetes |
en_US |
| dc.keywords |
Genome wide association |
en_US |
| dc.keywords |
Replication |
en_US |
| dc.keywords |
TCF7L2 |
en_US |
| dc.identifier.doi |
https://doi.org/10.1016/j.diabres.2012.09.044 |
en_US |
| dc.identifier.ctation |
Nemr, R., Turki, A., Echtay, A., Al-Zaben, G. S., Daher, H. S., Irani-Hakime, N. A., ... & Almawi, W. Y. (2012). Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects. Diabetes research and clinical practice, 98(3), e23-e27. |
en_US |
| dc.author.email |
rita.nemr@lau.edu.lb |
en_US |
| dc.identifier.tou |
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php |
en_US |
| dc.identifier.url |
https://www.sciencedirect.com/science/article/pii/S0168822712003671 |
en_US |
| dc.author.affiliation |
Lebanese American University |
en_US |