Use of extensively hydrolysed formula for refeeding neonates postnecrotising enterocolitis

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dc.contributor.author Matar, Maroun
dc.contributor.author Lapillonne, Alexandre
dc.contributor.author Adleff, Ariane
dc.contributor.author Chbihi, Marwa
dc.contributor.author Kermorvant-Duchemin, Elsa
dc.contributor.author Campeotto, Florence
dc.date.accessioned 2019-04-09T07:21:37Z
dc.date.available 2019-04-09T07:21:37Z
dc.date.copyright 2016 en_US
dc.date.issued 2019-04-09
dc.identifier.issn 2044-6055 en_US
dc.identifier.uri http://hdl.handle.net/10725/10375
dc.description.abstract Objective To evaluate the prevalence of and reasons for using extensively hydrolysed formulas (EHFs) of cow's milk proteins in the French neonatal units as well as the modality of their prescription for refeeding infants recovering from necrotising enterocolitis (NEC). Methods A multicentre nationwide cross-sectional study using a questionnaire to address the prevalence of use and the reasons for prescribing EHF in hospitalised neonates and to examine the protocols and the actual reasons for their use for refeeding infants in recovery from NEC. The questionnaire was sent to only 1 senior neonatologist in each neonatal unit included in the study. Results More than half of the French neonatal units participated in the survey. 91% of the surveyed units used EHF. Of 1969 infants hospitalised on the day the survey was run, 12% were fed on an EHF. 11% of the EHF prescriptions were due to previous NEC. The main reasons for using an EHF to feed infants post-NEC were the absence of human milk (75%) and surgical management of NEC (17%). When given, EHF was mainly prescribed for a period varying between 15 days and 3 months. None of the involved units continued using the EHF after 6 months of age. More than half of the surveyed units acknowledged hospitalising infants for the initiation of weaning EHF but only 21% of them tested these infants for cow's milk allergy. Conclusions The prevalence of EHF use in the French neonatal units is high. Refeeding infants post-NEC is one of the main reasons for such a high prevalence. The main incentive for using an EHF is the absence of human breast milk, either maternal or donor. en_US
dc.language.iso en en_US
dc.title Use of extensively hydrolysed formula for refeeding neonates postnecrotising enterocolitis en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle a nationwide survey-based, cross-sectional study en_US
dc.author.school SOM en_US
dc.author.idnumber 201004811 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal BMJ Open en_US
dc.journal.volume 6 en_US
dc.journal.issue 7 en_US
dc.article.pages e008613 en_US
dc.identifier.ctation Lapillonne, A., Matar, M., Adleff, A., Chbihi, M., Kermorvant-Duchemin, E., & Campeotto, F. (2016). Use of extensively hydrolysed formula for refeeding neonates postnecrotising enterocolitis: a nationwide survey-based, cross-sectional study. BMJ open, 6(7), e008613. en_US
dc.author.email maroun.matar@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://bmjopen.bmj.com/content/6/7/e008613?utm_source=trendmd&utm_medium=cpc&utm_campaign=bmjopen&trendmd-shared=1&utm_content=Journalcontent&utm_term=TrendMDPhase4 en_US
dc.author.affiliation Lebanese American University en_US

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