Indwelling pleural catheters in hepatic hydrothorax

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dc.contributor.author Diab, Khalil
dc.contributor.author Kniese, Christopher
dc.contributor.author Ghabril, Marwan
dc.contributor.author Bosslet, Gabriel
dc.date.accessioned 2019-02-13T09:30:46Z
dc.date.available 2019-02-13T09:30:46Z
dc.date.copyright 2019 en_US
dc.date.issued 2019-02-13
dc.identifier.issn 1931-3543 en_US
dc.identifier.uri http://hdl.handle.net/10725/10027
dc.description.abstract Background Treatment of hepatic hydrothorax (HH) generally involves sodium restriction, diuretics, and serial thoracentesis. In more advanced cases, transjugular intrahepatic portosystemic shunt and liver transplantation may be required. Previously, indwelling tube drainage has been avoided due to concerns regarding high complication rates and overall poor outcomes. Recently, indwelling pleural catheters (IPCs) have been proposed as a novel treatment option for HH. Methods This study was a retrospective review of patients who had undergone IPC placement for HH over a 10-year period at a large liver transplant referral center. We tracked outcomes, including complication rates and liver transplantation, as well as biomarkers of nutritional status. Results Sixty-two patients underwent IPC placement between 2007 and 2017, with 33 IPCs (53%) placed as a bridge to liver transplantation. Complications were recorded in 22 patients (36%); empyema was the most common, diagnosed in 10 patients (16.1%). Ten patients evaluated for liver transplantation underwent successful transplantation following IPC placement. There were statistically significant decreases in both BMI and serum albumin levels following IPC placement. Conclusions IPCs represent a potential treatment for refractory HH and should be used with caution in patients eligible for liver transplantation. Ideally, IPC use for these patients would be evaluated by a multidisciplinary team. IPC use may lead to small decreases in BMI and serum albumin levels in patients over time. en_US
dc.language.iso en en_US
dc.title Indwelling pleural catheters in hepatic hydrothorax en_US
dc.type Article en_US
dc.description.version Published en_US
dc.title.subtitle a single-center series of outcomes and complications en_US
dc.author.school SOM en_US
dc.author.idnumber 201900605 en_US
dc.author.department N/A en_US
dc.description.embargo N/A en_US
dc.relation.journal Chest en_US
dc.journal.volume 155 en_US
dc.journal.issue 2 en_US
dc.article.pages 307-314 en_US
dc.keywords Empyema en_US
dc.keywords Hepatic hydrothorax en_US
dc.keywords Indwelling pleural catheter en_US
dc.keywords Liver transplant en_US
dc.identifier.doi https://doi.org/10.1016/j.chest.2018.07.001 en_US
dc.identifier.ctation Kniese, C., Diab, K., Ghabril, M., & Bosslet, G. (2019). Indwelling pleural catheters in hepatic hydrothorax: a single-center series of outcomes and complications. Chest, 155(2), 307-314. en_US
dc.author.email khalil.diab@lau.edu.lb en_US
dc.identifier.tou http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php en_US
dc.identifier.url https://www.sciencedirect.com/science/article/pii/S0012369218310535 en_US
dc.orcid.id https://orcid.org/0000-0001-9255-7575 en_US
dc.author.affiliation Lebanese American University en_US

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