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Browsing by Subject "Ruthenium compounds"

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The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells

Fayad, Christelle (Lebanese American University, 2020-10-27)

Ruthenium complexes have been recently reported as potential chemotherapeutic agents that offer tumor selectivity and low tumor resistance. Photoactivated chemotherapy consists of introducing a ‘prodrug’ that dissociates ...
Evaluation of light-activated Ru(II) prodrugs and their photoproducts as potential anti-cancer agents

Elias, Maria (Lebanese American University, 2020-12-22)

Photoactivated chemotherapy (PACT) has emerged as a new method for targeted cancer therapy. Strained ruthenium based complexes with octahedral geometry may undergo ligand dissociation once irradiated, forming aquated ...
Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)

Azar, Daniel Fadi (Lebanese American University, 2016-04-06)

Acute myeloid leukemia (AML) is a class of hematopoietic malignancies that is characterized by the accumulation of abnormally differentiated myeloid cells and their infiltration into the bone marrow, blood and other tissues. ...
Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016)

Farhat, Stephanie Roy (Lebanese American University, 2016-12-08)

Cancer incidence has been increasing worldwide in the last few decades. Solid tumors are hard to treat, primarily due to drug resistance as well as to the struggle in delivering the drugs specifically to the tumor. Various ...

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