Browsing by Subject "Face -- Abnormalities -- Genetic aspects"

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Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development

Al Saneh, Mounir (Lebanese American University, 2021-03-12)

Cleft lip and/or palate (CL/P) affects on average 1 in 700 live births and is considered to be the most common congenital craniofacial birth defect (Setó-Salvia and Stanier 2014). It results from a failure in the lip buds ...
Dissection of the Genetic and Molecular Pathways of Cleft Lip and Palate

Hatoum, Jinine (Lebanese American University, 2021-05-20)

Cleft lip and palate (CLP) is a congenital anomaly affecting the lips and oral cavity and known to have an impact on the quality of life of the individuals who have it. This disease is known to be caused by both environmental ...
Orofacial Clefts

El Baba, Nada (Lebanese American University, 2021-05-09)

During embryogenesis, orofacial development takes place whereby cells migrate to their intended destinations to form the face of the fetus. Sometimes, cells of the palatal shelves and the lip buds do not properly migrate, ...

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