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Browsing by Author "Whelan, Amanda N."

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Metal-catalysed tandem metathesis-hydrogenation reactions for the synthesis of carba analogues of cyclic peptides

Elaridi, Jomana; Whelan, Amanda N.; Mudler, Roger J.; Robinson, Andrea J.; Jackson, W. Roy (2015-12-22)

Dicarba cyclic peptide analogues of the cystine-containing octapeptides octreotide, lanreotide, and vapreotide, all known somatostatin analogues, have been synthesized via an on-resin homogeneous metal-catalysed sequence ...
A tandem metathesis–hydrogenation route to dicarba analogues of cystine-containing cyclic peptides

Elaridi, Jomana; Whelan, Amanda N.; Harte, Michael; Smith, Suzanne V.; Jackson, W. Roy; Robinson, Andrea J. (2015-12-22)

Dicarba cyclic peptide analogues of the cyclic peptide octreotide have been synthesised in good yields using a single pot, on resin, tandem homogeneous metal-catalysed metathesis–hydrogenation sequence.

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