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Browsing by Author "Wang, Huamin"

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Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases

Ribero, David; Wang, Huamin; Donadon, Matteo; Zorzi, Daria; Thomas, Melanie; Eng, Cathy; Chang, David; Curley, Steven; Abdalla, Eddie; Ellis, Lee; Vauthey, Nicolas (2015-11-16)

BACKGROUND. The current study evaluated the effect of bevacizumab added to fluoropyrimidine-plus-oxaliplatin (5FU/OX) chemotherapy for colorectal liver metastases (CLM) on the pathologic response and nontumorous liver ...
Effect of Neoadjuvant Chemoradiation and Surgical Technique on Recurrence of Localized Pancreatic Cancer

Katz, Matthew; Wang, Huamin; Balachandran, Aparna; Bhosale, Priya; Crane, Christopher; Wang, Xuemei; Pisters, Peter; Lee, Jeffrey; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wolff, Robert; Abbruzzese, James; Varadhachary, Gauri; Chopin-Laly, Xavier; Chamsangavej, Chulsip; Fleming, Jason (2015-11-20)

Objectives To determine the influence of neoadjuvant chemoradiation and standardized dissection of the superior mesenteric artery upon the oncologic outcome of patients with localized pancreatic adenocarcinoma. Methods One ...
Impact of Resection Status on Pattern of Failure and Survival After Pancreaticoduodenectomy for Pancreatic Adenocarcinoma

Raut, Chandrajit; Tseng, Jennifer; Sun, Charlotte; Wang, Huamin; Wolff, Robert; Crane, Christopher; Vauthey, Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-16)

Objective: To better understand the impact of a microscopically positive margin (R1) on patterns of disease recurrence and survival after pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma. Summary Background ...
Long-Term Survival After Multidisciplinary Management of Resected Pancreatic Adenocarcinoma

Katz, Matthew; Wang, Huamin; Fleming, Jason; Sun, Charlotte; Hwang, Rosa; Wolff, Robert; Varadhachary, Gauri; Abbruzzese, James; Crane, Christopher; Krishnan, Sunil; Vauthey, Jean-Nicolas; Abdalla, Eddie; Lee, Jeffrey; Pisters, Peter; Evans, Douglas (2015-11-17)

Introduction Actual 5-year survival rates of 10–18% have been reported for patients with resected pancreatic adenocarcinoma (PC), but the use of multimodality therapy was uncommon in these series. We evaluated long-term ...
Pathologic Response to Preoperative Chemotherapy

Blazer III, Dan; Kishi, Yoji; Maru, Dipen; Shin Chun, Yun; Overman, Micheal; Fogelman, David; Eng, Cathy; Chang, David; Wang, Huamin; Zorzi, Daria; Ribero, Dario; Ellis, Lee; Glover, Katrina; Wolff, Robert; Curley, Steven; Abdalla, Eddie; Vauthey, Nicolas (2015-11-16)

Purpose The primary goal of this study was to evaluate whether pathologic response to chemotherapy predicts patient survival after preoperative chemotherapy and resection of colorectal liver metastases (CLM). The secondary ...
Post-Therapy Pathologic Stage and Survival in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemoradiation

Estrella, Jeannelyn; Rashid, Asif; Fleming, Jason; Katz, Matthew; Lee, Jeffrey; Wolff, Robert; Varadhachary, Gauri; Pisters, Peter; Abdalla, Eddie; Vauthey, Jean-Nicolas; Wang, Hua; Gomez, Henry; Evans, Douglas; Abbruzzese, James; Wang, Huamin (2015-11-20)

BACKGROUND: Neoadjuvant chemoradiation before surgery is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC). However, analysis of prognostic factors is limited for patients with PDAC treated with ...
Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head

Varadhachary, Gauri; Wolff, Robert; Crane, Christopher; Sun, Charlotte; Lee, Jeffrey; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Wang, Huamin; Staerkel, Gregg; Ross, William; Tamm, Eric; Bhosale, Priya; Krishnan, Sunil; Das, Prajnan; Ho, Linus; Xiong, Henry; Abbruzzese, James; Evans, Douglas (2015-11-17)

Purpose We conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy (PD) for patients with stage I/II pancreatic adenocarci ...
Serum CA 19-9 as a Marker of Resectability and Survival in Patients with Potentially Resectable Pancreatic Cancer Treated with Neoadjuvant Chemoradiation

Katz, Matthew; Varadhachary, Gauri; Fleming, Jason; Wolff, Robert; Lee, Jeffrey; Pisters, Peter; Vauthey, Jean-Nicolas; Abdalla, Eddie; Sun, Charlotte; Wang, Huamin; Crane, Christopher; Lee, Jeffrey; Tamm, Eric; Abbruzzese, James; Evans, Douglas (2015-11-19)

Purpose The role of carbohydrate antigen (CA) 19-9 in the evaluation of patients with resectable pancreatic cancer treated with neoadjuvant therapy prior to planned surgical resection is unknown. We evaluated CA 19-9 as ...
Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis

Rubbia-Brandt, Laura; Lauwers, Gregory; Wang, Huamin; Majno, Pietro; Tanabe, Kenneth; Zhu, Andrew; Brezault, Catherine; Soubrane, Olivier; Abdalla, Eddie; Vauthey, Jean-Nicolas; Mentha, Gilles; Terris, Benoit (2015-11-19)

Rubbia-Brandt L, Lauwers G Y, Wang H, Majno P E, Tanabe K, Zhu A X, Brezault C, Soubrane O, Abdalla E K, Vauthey J-N, Mentha G & Terris B (2010) Histopathology56, 430–439 Sinusoidal obstruction syndrome and nodular ...
Tumor Thickness at the Tumor-normal Interface: A Novel Pathologic Indicator of Chemotherapy Response in Hepatic Colorectal Metastases

Maru, Dipen; Kopetz, Scott; Boonsirikamcha, Piyaporn; Agarwal, Atin; Chun, Yun Shin; Wang, Huamin; Abdalla, Eddie; Kaur, Harmeet; Charnsangavej, Chusilp; Vauthey, Jean-Nicolas; Loyer, Evelyne (2015-11-19)

Background: Progress in the treatment of hepatic colorectal metastases (HCRM) demands pathologic indicators of therapy response. We observed that a majority of residual tumor cells are seen at the tumor-normal interface ...

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