Browsing by Author "Viar, Kenneth E."

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Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis

Basting, Tyler M.; Burke, Peter G. R.; Kanbar, Roy; Viar, Kenneth E.; Stornetta, Daniel S.; Stornetta, Ruth L.; Guyenet, Patrice G. (2016-10-11)

In conscious mammals, hypoxia or hypercapnia stimulates breathing while theoretically exerting opposite effects on central respiratory chemoreceptors (CRCs). We tested this theory by examining how hypoxia and hypercapnia ...
Selective optogenetic stimulation of the retrotrapezoid nucleus in sleeping rats activates breathing without changing blood pressure or causing arousal or sighs

Burke, Peter G. R.; Kanbar, Roy; Viar, Kenneth E.; Stornetta, Ruth L.; Guyenet, Patrice G. (2016-10-11)

Combined optogenetic activation of the retrotrapezoid nucleus (RTN; a CO2/proton-activated brainstem nucleus) with nearby catecholaminergic neurons (C1 and A5), or selective C1 neuron stimulation, increases blood pressure ...
State‐dependent control of breathing by the retrotrapezoid nucleus

Burke, Peter G. R.; Kanbar, Roy; Basting, Tyler M.; Hodges, Walter M.; Viar, Kenneth E.; Stornetta, Ruth L.; Guyenet, Patrice G. (2016-10-11)

Breathing has different characteristics during quiet wake, non-REM or REM sleep, including variable dependence on PCO2 . We investigated whether the retrotrapezoid nucleus (RTN), a proton-sensitive structure that mediates ...

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