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Browsing by Author "Thomas, Melanie"

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Browsing by Author "Thomas, Melanie"

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  • Association between hypothyroidism and hepatocellular carcinoma 
    Hassan, Manal; Kaseb, Ahmed; Li, Donghui; Vauthey, Jean-Nicolas; Thomas, Melanie; Curley, Steven; Spitz, Margaret; Sherman, Steven; Abdalla, Eddie; Davila, Marta; Lozano, Richard; Hassan, Deena; Wenyaw, Chan; Brown, Thomas; Abbruzzese, James; Patt, Yehuda (2015-11-17)
    Thyroid hormones play an essential role in lipid mobilization, lipid degradation, and fatty acid oxidation. Hypothyroidism has been associated with nonalcoholic steatohepatitis; however, the association between thyroid ...
  • Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases 
    Ribero, David; Wang, Huamin; Donadon, Matteo; Zorzi, Daria; Thomas, Melanie; Eng, Cathy; Chang, David; Curley, Steven; Abdalla, Eddie; Ellis, Lee; Vauthey, Nicolas (2015-11-16)
    BACKGROUND. The current study evaluated the effect of bevacizumab added to fluoropyrimidine-plus-oxaliplatin (5FU/OX) chemotherapy for colorectal liver metastases (CLM) on the pathologic response and nontumorous liver ...
  • Curing hepatocellular carcinomatosis with biologic therapy and surgery 
    Thomas, Melanie; Tetzlaff, Eric; Lozano, Richard; Samp, Leigh; Butler, Charles; Gannon, Christopher; Hamilton, Stanley; Vauthey, Jean-Nicolas; Abdalla, Eddie (2015-11-17)
    Hepatocellular carcinoma (HCC) that present as hemoperitoneum are uncommon, often recur as peritoneal carcinomatosis, and have poor prognosis. Systemic chemotherapies are minimally effective in advanced HCC and less so as ...
  • Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women 
    Hassan, Manal; Spitz, Margaret; Thomas, Melanie; El-Deeb, Adel; Glover, Katrina; Nguyem, Nga; Chan, Wenyaw; Kaseb, Ahmed; Curley, Steven; Vauthey, Nicolas; Ellis, Lee; Abdalla, Eddie; Lozano, Richard; Patt, Yehuda; Brown, Thomas; Abbruzzese, James; Li, Donghui (2015-11-17)
    The International Agency for Research on Cancer has declared smoking to be a risk factor for hepatocellular carcinoma (HCC). However, passive exposure to cigarette smoke and use of noncigarette tobacco products on the risk ...
  • Extrahepatic Bile Duct Adenocarcinoma 
    Borghero, Yerko; Crane, Christopher; Szklaruk, Janio; Oyarzo, Mauricio; Curley, Steven; Pisters, Peter; Evans, Douglas; Abdalla, Eddie; Thomas, Melanie; Das, Prajnan; Wistuba, Ignacio; Krishnan, Sunil; Vauthey, Nicolas (2015-11-16)
    Background Patients with resected extrahepatic bile duct adenocarcinoma who have microscopically positive resection margins and/or pathologic locoregional nodal involvement (R1pN1) have a high-risk of locoregional recurrence, ...
  • Liver resection in the treatment of hepatocellular carcinoma 
    Abdalla, Eddie; Ribero, Dario; Thomas, Melanie; Vauthey, Nicolas (2015-11-12)
    Hepatocellular carcinoma is a leading cause of cancer death worldwide. Liver resection and liver transplantation remain the only options for cure. Since the indications for orthotopic liver transplantation are limited, ...