Bekdash, Amira; Abi-Habib, Ralph J.; Tanios, Rita; Stone, Everett; Georgiou, Georges; Frankel, Arthur E.; Kassab, Elias
(2015-12-01)
In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. Mononuclear cells and CD34+ blasts were not sensitive ...