LAUR Home
→
Browsing by Author

Browsing by Author "Taleb, Robin I."

Now showing items 1-15 of 15

Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells

Haykal, Tony; Nasr, Peter; Hodroj, Mohammad H.; Taleb, Robin I.; Sarkis, Rita; El Moujabber, Marvy Nadine; Rizk, Sandra (2019-12-03)

Annona cherimola Mill is a large green fruit with black seeds widely known to possess toxic properties due to the presence of Annonaceous acetogenins. The present study investigates the anti-cancer properties of an Annona ...
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways

Daaboul, Hamid E.; Daher, Costantine F.; Bodman-Smith, Kikki; Taleb, Robin I.; Shehaby, Wassim N.; Boulos, Joelle; Dagher, Carole; Mroueh, Mohamad A.; El-Sibai, Mirvat (2017-12-15)

Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses in vitro and in vivo anticancer activities. Chemical analysis of DCOE led to the isolation of β-2-himachalen-6-ol (HC) which exhibited ...
Assessment of Toxic Metals and Phthalates in Children’s Toys and Clays

Korfali, Samira I.; Taleb, Robin I.; Jurdi, Mey; Sabra, Rayan (2015-11-07)

Toxic metals and phthalates are introduced in the manufacturing of plastic toys and modeling clays. In Lebanon, inexpensive plastic toys and modeling clays (sold in dollar stores) are affordable and popular, and there is ...
Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population

Hariri, Essa; Abboud, Martine I.; Demerdjian, Sally; Korfali, Samira; Mroueh, Mohamad; Taleb, Robin I. (2016-10-13)

The present study aims to quantify acrylamide and metals in potato and corn chips and to determine their carcinogenic and neurotoxic risks. Gas chromatography mass spectrometry analysis revealed that the average acrylamide ...
The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis

Daaboul, Hamid E.; Dagher, Carole; Taleb, Robin I.; Bodman-Smith, Kikki; Shebaby, Wassim N.; El-Sibai, Mirvat; Mroueh, Mohamad A.; Daher, Costantine F. (2019-10-08)

β-2-himachalen-6-ol (HC), a novel sesquiterpene derived from Lebanese wild carrot, was shown to possess a remarkable anticancer activity. The present study investigates the in vitro anticancer activity of HC and its effect ...
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells

Shebaby, Wassim N.; Mroueh, Mohammad; Bodman-Smith, Kikki; Mansour, Anthony; Taleb, Robin I.; Daher, Costantine F.; El-Sibai, Mirvat (2016-05-16)

Background Daucus carota L.ssp.carota (wild carrot), an herb used in folk medicine worldwide, was recently demonstrated to exhibit anticancer activity. In this study we examined the anticancer effect of Daucus carota oil ...
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways

Shehaby, Wassim N.; Bodman-Smith, K.B.; Mansour, Anthony; Mroueh, Mohamad; Taleb, Robin I.; El-Sibai, Mirvat; Daher, Costantine F. (2015-12-17)

Daucus carota L. ssp. carota (Apiacea, wild carrot, Queen Anne's lace) has been used in folk medicine throughout the world and recently was shown to possess anticancer and antioxidant activities. This study aims to determine ...
Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells

Zgheib, Perla; Daher, Costantine F.; Mroueh, Mohamad; Nasrallah, Anita; Taleb, Robin I.; El-Sibai, Mirvat (2017-02-08)

Daucus carota (DC) is a herb used in folklore medicine in Lebanon to treat numerous diseases including cancer. Recent studies in our laboratory on DC oil and its fractions revealed potent anticancer activities in vitro and ...
Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex

Mehanna, Stephanie; Mansour, Najwa; Audi, Hassib; Bodman-Smith, Kikki; Mroueh, Mohamad A.; Taleb, Robin I.; Daher, Costantine F.; Khnayzer, Rony S. (2019-10-01)

The use of ruthenium complexes as chemotherapeutic agents has been recently explored as one of the alternatives to conventional treatments. In the present study, two Ru(II) polypyridyl complexes were synthesized and ...
Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro

El Khoury, Marianne; Haykal, Tony; Hodroj, Mohammad H.; Abou Najem, Sonia; Sarkis, Rita; Taleb, Robin I.; Rizk, Sandra (2020-07-23)

Malva pseudolavatera Webb & Berthel. is a plant from the Malvaceae family that has long been included in the human diet due to its various curative effects. Many plant leaf extracts from the various species of Malva genus ...
Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles

Taleb, Robin I.; Wheate, Nial J.; Krause-Heuer, Anwen M.; Cook, Rebekah L.; Wang, Shaoyu; Higgins, Vincent J.; Aldrich-Wright, Janice R. (2016-04-06)

Platinum(II)-based DNA intercalators where the intercalating ligand is 1,10-phenanthroline or a phenanthroline derivative and where the ancillary ligand is either achiral (e.g. ethylenediamine) or chiral (e.g. ...
Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines

Mansour, Najwa; Mehanna, Stephanie; Mroueh, Mohamad A.; Audi, Hassib; Bodman-Smith, Kikki; Daher, Costantine F.; Taleb, Robin I.; El-Sibai, Mirvat; Khnayzer, Rony S. (2019-10-01)

The current study investigates [Ru(bipy)2(dpphen)]Cl2 [where bipy = 2,2′‐bipyridine and dpphen = 2,9‐diphenyl‐1,10‐phenanthroline] (complex 1) for photoactivatable chemotherapy (PACT) application on five cancer cell lines. ...
The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines

Ammoury, Carl; Younes, Maria; El Khoury, Marianne; Hodroj, Mohammad H.; Haykal, Tony; Nasr, Peter; Sily, Marilyne; Taleb, Robin I.; Sarkis, Rita; Khalife, Rana; Rizk, Sandra (2020-07-24)

Background The edible fruit Annona cherimola has previously shown many nutritional and medicinal properties. The current study evaluates the anti-cancer and anti-proliferative properties of Annona cherimola ethanolic leaf ...
β-2-himachalen-6-ol

Taleb, Robin I.; Najm, Paul; Shebaby, Wassim; Boulos, Joelle C.; Demirdjian, Sally; Hariri, Essa; El-Sibai, Mirvat; Daher, Costantine; Mroueh, Mohamad (2016-10-13)

Daucus carota ssp. carota, also known as wild carrot, is a commonly used herb in Lebanese folk medicine to treat several ailments including cancer. Previous studies in our laboratories showed that the Daucus carota oil ...
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo

Daaboul, Hamid E.; Daher, Costantine F.; Taleb, Robin I.; Boulos, Joelle; Bodman‐Smith, Kikki; Boukamp, Petra; Shebaby, Wassim N.; Dagher, Carol; El-Sibai, Mirvat; Mroueh, Mohamad A. (2017-12-15)

Background Previous studies in our laboratory showed that Daucus carota oil extract (DCOE) possesses remarkable in-vitro anticancer activity and antitumour promoting effect against DMBA/TPA skin carcinogenesis in mice. ...

Now showing items 1-15 of 15

Search LAUR

Advanced Search

Browse

All of LAUR

Browsing by Author "Taleb, Robin I."

LAUR Repository

Browsing by Author "Taleb, Robin I."

Search LAUR

Browse

All of LAUR

My Account