Browsing by Author "Steven Shaw, S. W."

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Local Over-Expression of VEGF-DDNDC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis

Abi Nader, Khalil; Mehta, Vedanta; Shangaris, Panicos; Steven Shaw, S. W.; Filippi, Elisa; Benjamin, Elizabeth (2016-06-08)

Background The normal development of the uteroplacental circulation in pregnancy depends on angiogenic and vasodilatory factors such as vascular endothelial growth factor (VEGF). Reduced uterine artery blood flow (UABF) ...
Telemetric monitoring of fetal blood pressure and heart rate in the freely moving pregnant sheep

Abi Nader, Khalil; Mehta, Vedanta; Steven Shaw, S. W.; Bellamy, Tom; Smith, Neil; Millross, Laura (2016-06-08)

Remote telemetric monitoring of fetal haemodynamics in pregnant sheep would allow unrestricted animal movement, minimize suffering and distress, and improve animal welfare, while enhancing the quality of data collected. ...
Ultrasonographic Development of the Fetal Sheep Stomach and Evaluation of Early Gestation Ultrasound-guided In Utero Intragastric Injection

Abi Nader, Khalil; David, Anna L.; Weisz, Boaz; Steven Shaw, S. W.; Themis, Michael; Cook, Terence (2016-06-08)

Objective Safely targeting the fetal gastrointestinal tract during early gestation is essential to develop effective prenatal gene therapy for gastrointestinal diseases. In this study, we aimed to characterize the development ...

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