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Browsing by Author "Sevick-Muraca, Eva M."

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Browsing by Author "Sevick-Muraca, Eva M."

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  • Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer 
    Sampath, Lakshmi; Kwon, Sunkuk; Ke, Shi; Wang, Wei; Schiff, Rachel; Mawad, Michel E.; Sevick-Muraca, Eva M. (2019-07-08)
    Overexpression of the human epidermal growth factor receptor (HER) family has been implicated in cancer because of its participation in signaling pathways regulating cellular proliferation, differentiation, motility, and ...
  • Imaging of lymph flow in breast cancer patients after microdose administration of a near-infrared fluorophore 
    Sevick-Muraca, Eva M.; Sharma, Ruchi; Rasmussen, John C.; Marshall, Milton V.; Wendt, Juliet A.; Pham, Joang Q.; Bonefas, Elizabeth; HHouston, Jessica P.; Sampath, Lakshmi; Adams, Kristen E.; Blanchard, Darlene Kay; Fisher, Ronald E.; Chiang, Stephen B.; Elledge, Richard; Mawad, Michel E. (2019-07-08)
    Purpose: To prospectively demonstrate the feasibility of using indocyanine green, a near-infrared (NIR) fluorophore at the minimum dose needed for noninvasive optical imaging of lymph nodes (LNs) in breast cancer patients ...
  • A new optical and nuclear dual-labeled imaging agent targeting interleukin 11 receptor alpha-chain 
    Wang, Wei; Ke, Shi; Kwon, Sunkuk; Yallampalli, Sasidhar; Cameron, Arlin G.; Adams, Kristen E.; Mawad, Michel E.; Sevick-Muraca, Eva M. (2019-07-08)
    Optical imaging has great potential for studying molecular recognitions both in vivo and in vitro, yet nuclear imaging is the most effective clinical molecular imaging modality. The combination of optical and nuclear imaging ...
  • Quantitative imaging of lymph function 
    Sharma, Ruchi; Wang, Wei; Rasmussen, John C.; Joshi, Amit; Houston, Jessica P.; Adams, Kristen E.; Cameron, Arlin; Ke, Shi; Kwon, Sunkuk; Mawad, Michel E.; Sevick-Muraca, Eva M. (2019-07-08)
    Abstract Functional lymphatic imaging was demonstrated in the abdomen and anterior hindlimb of anesthetized, intact Yorkshire swine by using near-infrared (NIR) fluorescence imaging following intradermal administration ...