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Browsing by Author "Sandler, Anthony D."

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Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant propertiesor radio-therapy resistance

Abou-Antoun, Tamara J.; Nazarian, Javad; Ghanem, Anthony; Vukmanovic, Stanislav; Sandler, Anthony D. (2019-11-07)

Despite significant advances in cancer treatment and management, more than 60% of patients with neuroblastoma present with very poor prognosis in the form of metastatic and aggressive disease. Solid tumors including ...
Reversible adaptive plasticity

Abou-Antoun, Thamara; Chakrabati, Lina; Vykmanovic, Stainslav; Sandler, Anthony D. (2016-09-27)

We describe a novel form of tumor cell plasticity characterized by reversible adaptive plasticity in murine and human neuroblastoma. Two cellular phenotypes were defined by their ability to exhibit adhered, anchorage ...

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