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Browsing by Author "Mikati, Mohamad A."

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Browsing by Author "Mikati, Mohamad A."

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  • Changes in sphingomyelinases, ceramide, Bax, Bcl2, and caspase-3 during and after experimental status epilepticus 
    Abi-Habib, Ralph; Mikati, Mohamad A.; Zeineh, Michel; El Hokayem, Jimmy; Rahmeh, Amal; El Sabban, Marwan; Usta, Julnar; Dbaibo, Ghassan (2015-11-30)
    Status epilepticus (SE) induces a number of events leading to programmed cell death (PCD). The aim of our work is to study the time sequence of activation of different factors in experimental SE (intraperitoneal kainic ...
  • Current and Emerging Therapies of Severe Epileptic Encephalopathies 
    Hani, Abeer J.; Mikati, Mohamad A. (2016-11-11)
    In this article, we review the treatment options for the pediatric epileptic encephalopathies and provide an update on the new and emerging therapies targeted at the underlying pathophysiology of many of these syndromes. ...
  • Epilepsy surgery in a developing country (Lebanon): ten years experience and predictors of outcome Remove selected 
    Mikati, Mohamad A.; Ataya, Nour; El-Ferezli, Jessica; Shamseddine, Alhan; Rahi, Amal; Herlopian, Aline; Kurdi, Rana; Bhar, Saleh; Hani, Abeer; Comair, Youssef G. (2016-11-11)
    We present our 10-year experience and preoperative predictors of outcome in 93 adults and children who underwent epilepsy surgery at the American University of Beirut. Presurgical evaluation included video-EEG monitoring, ...
  • Familial spinocerebellar degeneration with corneal dystrophy 
    Deeb, Mary E.; Der Kaloustian, Vazken M.; Jarudi, Nabil I.; Khoury, Muin J.; Afifi, Adel K.; Bahuth, Nadia B.; Shammas, John; Mikati, Mohamad A.; Opitz, John M.; Reynolds, James F. (2016-11-23)
    We report on two sisters born to normal but consanguineous parents, with the unusual combination of spinocerebellar degeneration and corneal dystrophy. Their manifestations include mental subnormality, bilateral corneal ...
  • Genetics of Pediatric Epilepsy 
    Hani, Abeer J.; Mikati, Husam M.; Mikati, Mohamad A. (2016-11-11)
  • Hippocampal Programmed Cell Death after Status Epilepticus 
    Abi-Habib, Ralph J.; Kobbeissi, Mohamad; Farhat, Firas; Dbaibo, Ghassan S.; Kurdi, Rana M.; Mikati, Mohamad A.; El Sabban, Marwan E.; Asaad, Wissal (2015-11-30)
    Summary:  Purpose: Status epilepticus (SE) can result in acute neuronal injury with subsequent long-term age-dependent behavioral and histologic sequelae. To investigate potential mechanisms that may underlie SE-related ...
  • Novel mutation causing partial biotinidase deficiency in a Syrian boy with infantile spasms and retardation 
    Mikati, Mohamad A.; Zalloua, Pierre; Karam, Pascale (2019-07-22)
    We report a case of partial biotinidase deficiency (plasma biotinidase levels: 1.30 nm/minute/mL) in a 7-month-old boy who presented with evidence of perinatal distress followed by developmental delay, hypotonia, seizures, ...