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Browsing by Author "Junen, Judith"

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Gender specific differences in levels of DNA methylation at selected loci from human total blood

El Maarri, Osman; Becker, Tim; Junen, Judith; Manzoor, Syed Saadi; Diaz-Lacava, Amalia (2017-09-13)

Abnormal patterns of DNA methylation are observed in many diseases such as tumors and imprinting disorders. Little is known about inter-individual and gender specific variations. Here, we report on accurate and sensitive ...
A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation

El Maarri, Osman; Kareta, Micheal S.; Mikeska, Thomas; Becker, Tim; Diaz-Lacava, Amalia; Junen, Judith; Nusgen, Nicole; Behne, Frank; Wienker, Thomas; Waha, Andreas (2017-09-14)

Causes underlying inter-individual variations in DNA methylation profiles among normal healthy populations are not thoroughly understood. To investigate the contribution of genetic variation in DNA methyltransferase (DNMT) ...

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