Background Topotecan (TP) is an anticancer drug acting as topoisomerase I inhibitor that is used in the treatment of many types of cancers including leukemia, but it has significant side effects. Andrographolide, a compound ...

n nature, vitamin E derivatives can exist in eight different forms which are grouped in two main categories, namely Tocopherols (TP) and Tocotrienols (T3). Each category includes four derivatives which differ in the position ...

Topotecan, a topoisomerase I inhibitor, is an anticancer drug widely used in the therapy of lung, ovarian, colorectal, and breast adenocarcinoma. Due to the primary dose-limiting toxicity of topotecan, which is myelosuppressive, ...