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Browsing by Author "Hanna, Samer"

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Browsing by Author "Hanna, Samer"

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  • Deletion of the Candida albicans PIR32 Results in Increased Virulence, Stress Response, and Upregulation of Cell Wall Chitin Deposition 
    Bahnan, Wael; Koussa, Joseph; Younes, Samer; Abi Rizk, Marybel; Khalil, Bassem; El Sitt, Sally; Hanna, Samer; El-Sibai, Mirvat; Khalaf, Roy A. (2016-03-18)
    Candida albicans is a common opportunistic pathogen that causes a wide variety of diseases in a human immunocompromised host leading to death. In a pathogen, cell wall proteins are important for stability as well as for ...
  • DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma 
    El-Sitt, Sally; Khalil, Bassem D.; Hanna, Samer; El-Sabban, Marwan; Fakhreddine, Najla; El-Sibai, Mirvat (2015-11-04)
    Astrocytomas are tumors occurring in young adult-hood. Astrocytic tumors can be classified into four grades according to histologic features: grades I, II, III and grade IV. Malignant tumors, those of grades III and IV, ...
  • Effect of StarD13 on colorectal cancer proliferation, motility and invasion 
    Nasrallah, Anita; Saykali, Bechara; Hanna, Samer; El-Sibai, Mirvat (2017-02-08)
    Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. Many mutations are acquired which leads to ...
  • The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility 
    Khalil, Bassem D.; Hanna, Samer; Saykali, Bechara A.; El-Sitt, Sally; Nasrallah, Anita; Marston, Daniel; El-Sabban, Marwan; Hahn, Klaus M.; Symons, Marc; El-Sibai, Mirvat (2017-02-08)
    Malignant astrocytomas are highly invasive into adjacent and distant regions of the normal brain. Rho GTPases are small monomeric G proteins that play important roles in cytoskeleton rearrangement, cell motility, and tumor ...
  • Signaling networks of Rho GTPases in cell motility 
    Hanna, Samer; El-Sibai, Mirvat (2015-12-17)
    The last decades have witnessed an exponential increase in our knowledge of Rho GTPase signaling network which further highlighted the cross talk between these proteins and the complexity of their signaling pathways. In ...
  • StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion 
    Hanna, Samer; Khalil, Bassem; Nasrallah, Anita; Saykali, Bechara A.; Sobh, Rania; Nasser, Selim; El-Sibai, Mirvat (2015-12-18)
    Breast cancer is one of the most commonly diagnosed cancers in women around the world. In general, the more aggressive the tumor, the more rapidly it grows and the more likely it metastasizes. Members of the Rho subfamily ...