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Browsing by Author "Ghanem, Anthony"

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Browsing by Author "Ghanem, Anthony"

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  • Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling 
    Nasrallah, Patrick; Abou Haidar, Edwina; Stephan, Joseph S.; El Hayek, Lauretta; Karnib, Nabil; Khalifeh, Mohamad; Barmo, Nour; Jabre, Vanessa; Houbeika, Rouba; Ghanem, Anthony; Nasser, Jason; Zeeni, Nadine; Bassil, Maya; F. Sleiman, Sama (2019-10-11)
    How individuals respond to chronic stress varies. Susceptible individuals ultimately develop depression; whereas resilient individuals live normally. In this study, our objective was to examine the effect of branched-chain ...
  • The combinatory effects of diet and exercise on BDNF gene expression 
    Bassil, Maya; Zeeni, Nadine; Sleiman, Sama; Abou Haidar, Edwina; Azar, Adriana; Ghanem, Anthony; Bassil, Katherine (2018-05-09)
    Brain Derived Neurotrophic Factor (BDNF) plays a critical role in the synaptic activity and plasticity of mature neurons and regulates the formation and maintenance of memory. Furthermore, human and mouse BDNF levels were ...
  • Epigenetic changes in diabetes 
    Stephan, Joseph S.; Al-Haddad, Rami; Karnib, Nabil; Abi Assaad, Rawad; Bilen, Yara; Emmanuel, Nancy; Ghanem, Anthony; Younes, Joe; Zibara, Victor; Sleiman, Sama F. (2016-12-15)
    The incidence of diabetes is increasing worldwide. Diabetes is quickly becoming one of the leading causes of death. Diabetes is a genetic disease; however, the environment plays critical roles in its development and ...
  • Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant propertiesor radio-therapy resistance 
    Abou-Antoun, Tamara J.; Nazarian, Javad; Ghanem, Anthony; Vukmanovic, Stanislav; Sandler, Anthony D. (2019-11-07)
    Despite significant advances in cancer treatment and management, more than 60% of patients with neuroblastoma present with very poor prognosis in the form of metastatic and aggressive disease. Solid tumors including ...