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Browsing by Author "El-Sitt, Sally"

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Browsing by Author "El-Sitt, Sally"

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  • DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma 
    El-Sitt, Sally; Khalil, Bassem D.; Hanna, Samer; El-Sabban, Marwan; Fakhreddine, Najla; El-Sibai, Mirvat (2015-11-04)
    Astrocytomas are tumors occurring in young adult-hood. Astrocytic tumors can be classified into four grades according to histologic features: grades I, II, III and grade IV. Malignant tumors, those of grades III and IV, ...
  • The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility 
    Khalil, Bassem D.; Hanna, Samer; Saykali, Bechara A.; El-Sitt, Sally; Nasrallah, Anita; Marston, Daniel; El-Sabban, Marwan; Hahn, Klaus M.; Symons, Marc; El-Sibai, Mirvat (2017-02-08)
    Malignant astrocytomas are highly invasive into adjacent and distant regions of the normal brain. Rho GTPases are small monomeric G proteins that play important roles in cytoskeleton rearrangement, cell motility, and tumor ...
  • The STAR of the DLC family 
    El-Sitt, Sally; El-Sibai, Mirvat (2015-12-17)
    RhoGTPases are defined as a family of 20 small G proteins playing important roles in almost every cellular process. RhoGTPases are guanine nucleotide-binding proteins existing in two forms: the active form which is GTP ...