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Browsing by Author "El Atat, Oula"

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Browsing by Author "El Atat, Oula"

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  • Metformin treatment inhibits motility and invasion of glioblastoma cancer cells 
    Al Hassan, Marwa; Fakhoury, Isabelle; El Masri, Zeinab; Ghazale, Noura; Dennaoui, Rayane; El Atat, Oula; Kanaan, Amjad; El-Sibai, Mirvat (2019-10-08)
    Glioblastoma multiforme (GBM) is one of the most common and deadliest cancers of the central nervous system (CNS). GBMs high ability to infiltrate healthy brain tissues makes it difficult to remove surgically and account ...
  • RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells 
    El Atat, Oula; Fakih, Amira; El-Sibai, Mirvat (2019-10-08)
    Angiogenesis is a hallmark of cancer cell malignancy. The role of the RHO family GTPase RHOG in angiogenesis in vascular endothelial cells has recently been elucidated. However, the regulation of RHOG during this process, ...
  • The Role of Rho GTPases in Motility and Invasion of Glioblastoma Cells 
    Al-Koussa, Houssam; El Atat, Oula; Jaafar, Leila; Tashjian, Hagop; El-Sibai, Mirvat (2020-05-01)
    Astrocytomas are primary malignant brain tumors that originate from astrocytes. Grade IV astrocytoma or glioblastoma is a highly invasive tumor that occur within the brain parenchyma. The Rho family of small GTPases, which ...