Milane, Aline; Fernandez, Christine; Dupuis, Luc; Buyse, Marion; Loeffler, Jean-Philippe; Farinotti, Robert; Meininger, Vincent; Bensimon, Gilbert
(2016-10-04)
The efflux pumps located at the blood–brain barrier (BBB) prevent drugs entering the brain. As such, efflux pumps are a major obstacle to drug brain distribution. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative ...